Results 31 to 40 of about 1,325,975 (331)

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Analytical Solutions To Boundary Value Problem Of Free Vibration Of Sandwich Thin Circular Plates With Discrete Elements

open access: yesInternational Journal of Applied Mechanics and Engineering, 2015
In the paper the influence function and the method of partial discretization in free axisymmetric vibration analysis of multilayered circular plates of constant and linearly variable thickness were presented.
K.K. Żur, J. Jaroszewicz, Ł. Dragun
doaj   +1 more source

Free boundaries in problems with hysteresis [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2015
Here, we present a survey concerning parabolic free boundary problems involving a discontinuous hysteresis operator. Such problems describe biological and chemical processes ‘with memory’ in which various substances interact according to hysteresis law.
D. E. Apushkinskaya, N. N. Uraltseva
openaire   +3 more sources

Free boundary problems involving singular weights [PDF]

open access: yesCommunications in Partial Differential Equations, 2020
In this paper we initiate the investigation of free boundary minimization problems ruled by general singular operators with $A_2$ weights. We show existence and boundedness of minimizers. The key novelty is a sharp $C^{1+ }$ regularity result for solutions at their singular free boundary points. We also show a corresponding non-degeneracy estimate.
Lamboley, Jimmy   +2 more
openaire   +3 more sources

Singular Perturbation Problem in Boundary/Fractional Combustion

open access: yes, 2015
Motivated by a nonlocal free boundary problem, we study uniform properties of solutions to a singular perturbation problem for a boundary-reaction-diffusion equation, where the reaction term is of combustion type.
Petrosyan, Arshak   +2 more
core   +3 more sources

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Ray methods for free boundary problems [PDF]

open access: yesQuarterly of Applied Mathematics, 2006
We discuss the use of the WKB ansatz in a variety of parabolic problems involving a small parameter. We analyse the Stefan problem for small latent heat, the Black–Scholes problem for an American put option, and some nonlinear diffusion equations, in each case constructing an asymptotic solution by the use of ray methods.
Addison, J, Howison, S, King, J
openaire   +5 more sources

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz   +3 more
wiley   +1 more source

A free boundary seepage problem through earth dam withan impermeable screen

open access: yesИзвестия высших учебных заведений: Проблемы энергетики, 2017
A water seepage problem through the rectangular earth dam with the presence of a vertical impermeable screen was studied in nonlinear formulation. A finite-difference scheme with a fixed mesh was used for discretization of mathematical equations with a ...
K. P. Kurtseva   +2 more
doaj   +1 more source

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