Results 111 to 120 of about 547,609 (262)

The therapeutic opportunities and pitfalls of using iron ion chelators to treat neurodegenerative diseases

FEBS Letters, EarlyView.
Although too much iron in the brain promotes neurodegeneration, iron ion chelators have had mixed effects in clinical trials. This review explains why; some chelators do not render the iron redox‐inactive (e.g., L1) whereas others do (e.g., desferrioxamine).
Barry Halliwell
wiley   +1 more source

Uninsured free clinic patients’ experiences and perceptions of healthcare services, community resources, and the Patient Protection and Affordable Care Act

Patient Experience Journal, 2016
Free clinics provide free or reduced fee healthcare to individuals who lack access to primary care and are socio-economically disadvantaged. There has been a paucity of free clinic research with the few studies employing a quantitative design.
Akiko Kamimura, Jeanie Ashby, Ha Trinh, Liana Prudencio, Anthony Mills, Jennifer Tabler, Maziar Nourian, Fattima Ahmed, Justine Reel   +8 more
doaj  

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Free and charitable clinics

Population Medicine, 2023
Julie Darnell, Nicole Lamoureux, Cat Hulburt, Julie Darnell   +3 more
openaire   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Characteristics of Patients with Dermatologic Conditions in a Student-Run Free Clinic: A Retrospective Study. [PDF]

J Stud Run Clin, 2023
Hammond AM, Smith KN, Welborn M, Dukharan V, Daga A, Warpinski C, Nguyen OT, Motwani K, Motaparthi K.   +8 more
europepmc   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

FEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee, Mingming Tong, Anna L. Gloyn   +2 more
wiley   +1 more source

Antibiotic appropriateness among patients experiencing homelessness at an interprofessional student-run free clinic. [PDF]

Antimicrob Steward Healthc Epidemiol
Laster O, Stewart MP, Lin KP, Carlson TJ.   +3 more
europepmc   +1 more source

Patient-Level Characteristics Associated with Tobacco Users and Nonusers at a Student-Run Free Clinic. [PDF]

South Med J, 2023
Magaldino A, Dang C, In E, Nguyen K, Nguyen OT, Motwani K, Feller DB.   +6 more
europepmc   +1 more source

Free Clinics for the Preschool Child [PDF]

American Journal of Public Health and the Nations Health, 1930
openaire   +2 more sources