Results 231 to 240 of about 171,167 (310)

Smart Integration of Structural Biology and Medicinal Chemistry to Unlock Target‐Driven Drug Discovery

Medicinal Research Reviews, EarlyView.
ABSTRACT To enhance drug discovery efforts, medicinal chemists should evaluate, filter, and utilize relevant structural information about target proteins. Acquiring and interpreting protein structures is crucial for elucidating ligand‐receptor interactions and addressing ADME‐related considerations, making it an essential aspect of medicinal chemistry.
Matteo Rossi Sebastiano, Giulia Apprato, Serena Francisco, Giuseppe Ermondi, Giulia Caron   +4 more
wiley   +1 more source

Preventing Free Flap Complications: Key Factors to Keep in Mind. [PDF]

J Surg Oncol
Kornmann J, Schug R, Huber L, Lammert A, Jungbauer F, Affolter A, Rotter N, Zaubitzer L, Bugia L, Beck G, Scherl C.   +10 more
europepmc   +1 more source

Numerical Insights Into the Resistance Reduction Mechanisms of Forward Tapered Transoms in High‐Speed Catamaran: A Computational Fluid Dynamics‐Based Study

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT This study investigates the hydrodynamic influence of forward transom tapering on a displacement catamaran hull using computational fluid dynamics (CFD) simulations. Five taper configurations ranging from a vertical transom base design to a fully tapered stern (1.00B) were evaluated over a wide Froude number range (Fr = .3 to 1.0).
Chalermkiat Nuchturee, Chairat Napasaksri, Ramil Kesvarakul, Sarawuth Srinakaew   +3 more
wiley   +1 more source

Medicare Utilization and Reimbursement Trends for Free Flaps in Otolaryngology, Plastic Surgery, and Maxillofacial Surgery

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Free flap procedures are important components of reconstructive surgery in otolaryngology, plastic surgery, and maxillofacial surgery. This research investigates trends in utilization, charges, and Medicare reimbursements for free flap procedures performed across these specialties.
Kyle Polen, Alan Napole, Gavin Turner, Robert M. Brody, Ryan M. Carey   +4 more
wiley   +1 more source

Clinical Value of Transcutaneous PCO₂ in Free Flap Blood Supply. [PDF]

J Clin Med
Liu F, Han N, Wang L, Dong J, Ruan M, Ying Y.   +5 more
europepmc   +1 more source

Hair Transplantation on Free Flap in a Patient with Malignant Scalp Neoplasms: A Case Report. [PDF]

Clin Cosmet Investig Dermatol
Shen H, Xu Y, Wang X, Zhang J.
europepmc   +1 more source

Phalloplasty as a treatment for severe penile insufficiency [PDF]

, 2008
Ceulemans, Peter, Cools, Martine, Hoebeke, Piet, Lumen, Nicolaas, Monstrey, Stan   +4 more
core   +1 more source

Utilization of Superficial Circumflex Iliac Artery Perforators for Hemiabdominal Free Flap Breast Reconstruction. [PDF]

Plast Reconstr Surg Glob Open
Bakovic MN, Daniel AA, Gary CS, Wallace SJ, Ranganath B.   +4 more
europepmc   +1 more source

Lower Eyelid and Cheek Reconstruction With the First Dorsal Metacarpal Artery Free Flap: A Case Report. [PDF]

Cureus
Díaz Hernández SA, Díaz Avila DV, López Gutiérrez D, Reynoso Campo R, Echeverria Desentis AE.   +4 more
europepmc   +1 more source