Results 81 to 90 of about 1,561,010 (263)

Behavior of Water Jet Accompanied with Air Suction

open access: yesJournal of Fluid Science and Technology, 2007
In order to atomize a liquid, the authors have investigated the behavior of air-water jets. In a series of experiments, we have discovered a strange phenomenon that the water jet accompanied with air suction from the free surface has made a periodic ...
Hironobu KAWAKAMI   +2 more
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Experimental and Field Investigation of the Use of Radial Gates as Flow Measurement Structures at Free and Submerged Flow Conditions

open access: yesمجله آب و خاک, 2014
The development of an enhanced approach for the use of radial gates as flow measurement structures is important in irrigation networks. In this study, new theoretical relationships were developed to estimate the discharge coefficient (Cd) for a single ...
Y. Aminpour   +3 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Free flow velocity of high-drag particles in liquid

open access: yesИнженерно-строительный журнал, 2012
This article discusses the phenomenon of free movement of buffle bodies in a fluid. The basis of hydraulic design of many technical devices (septic tanks, aeration and flotation chambers, hydro-and pneumatic transport, etc.) is the deposition rate (or ...
Mikhalev M.A.
doaj  

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Panelization study for free surface potential flow computation

open access: yesAnnals of "Dunărea de Jos" University of Galaţi: Fascicle XI Shipbuilding, 2017
The present work concerns the space discretion of the free-surface potential flow computation based boundary element method. A series of systematically sensitivity studies on the number of panels and distribution on the body and on the free surface have ...
Florin Pacuraru
doaj  

Determining Free-Flow Speed on Different Classes of Rural Two-Lane Highways

open access: yesPromet (Zagreb), 2023
Current analytical free-flow speed models consider all rural two-lane highways as the same road type despite their different functional significance in the network.
Nemanja Stepanović   +2 more
doaj  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

open access: yesFEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante   +10 more
wiley   +1 more source

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