Results 101 to 110 of about 9,681,538 (276)

Antidiabetic Medicinal Plants Used by the Basotho Tribe of Eastern Free State: A Review

open access: yesJournal of Diabetes Research, 2016
Diabetes mellitus (DM) belongs to the group of five leading important diseases causing death globally and remains a major health problem in Africa. A number of factors such as poverty, poor eating habit, and hormonal imbalance are responsible for the ...
Fatai Oladunni Balogun   +2 more
doaj   +1 more source

FOLDING FREE-GROUP AUTOMORPHISMS [PDF]

open access: yesThe Quarterly Journal of Mathematics, 2013
We describe an algorithm that uses Stallings' folding technique to decompose an element of $Aut(F_n)$ as a product of Whitehead automorphisms (and hence as a product of Nielsen transformations.) We use this to give an alternative method of finding a finite generating set for the subgroup of $Aut(F_n)$ that fixes a subset $Y$ of the basis elements, and ...
openaire   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Mechanisms of orphan nuclear receptor Nur77 in liver health, disease, and therapeutic potential: narrative review

open access: yesnpj Gut and Liver
The nuclear receptor (NR) superfamily consists of the orphan NR subgroup NR4A, of which Nur77, an immediate early response gene, plays a crucial role in liver physiology and pathophysiology.
Ola Alsharif, Krista Rombouts
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Establishment and Characterization of Callus and Cell Suspension Cultures of Selected Sorghum bicolor (L.) Moench Varieties: A Resource for Gene Discovery in Plant Stress Biology

open access: yesAgronomy, 2019
Sorghum, a naturally drought tolerant crop, is genetically diverse and provides a wide gene pool for exploitation in crop breeding. In this study, we experimentally assessed friable callus induction rates of seven sorghum varieties using shoot explant ...
Elelwani Ramulifho   +5 more
doaj   +1 more source

Free groups in lattices [PDF]

open access: yesGeometry & Topology, 2009
This version corrects a few typos.
openaire   +4 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Automorphism Groups of Free Soluble Groups

open access: yesJournal of Algebra, 1995
Let \(F\) be a free soluble group of derived length \(k\) and rank \(m\) and \(\Phi\) any group of automorphisms of \(F\). The author's Theorem A is that \(\Phi\) contains either a free subgroup of rank 2 or a soluble normal subgroup of finite index and derived length bounded by functions of \(k\) and \(m\) only.
openaire   +2 more sources

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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