Results 131 to 140 of about 3,616,669 (319)
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Community Festival vendors [PDF]
, 1975 Photograph showing ComFest vendors at a booth set up along the street, likely in June 1980, taken for the Columbus Free Press. Their sign reads "Middle Earth Terrariums." ComFest, short for "Community Festival," is an annual volunteer-run event in ...
Columbus Free Press (Publisher)
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Agronomy, 2019 Sorghum, a naturally drought tolerant crop, is genetically diverse and provides a wide gene pool for exploitation in crop breeding. In this study, we experimentally assessed friable callus induction rates of seven sorghum varieties using shoot explant ...
Elelwani Ramulifho +5 more
doaj +1 more source
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
1986 Columbus Gay Pride Parade photograph [PDF]
, 1986 A crowd watches three speakers or performers at the annual Gay Pride Parade (identified on the reverse as the "Lesbian/Gay Freedom Parade") at the Riverfront Amphitheater in downtown Columbus, Ohio, June 29, 1986.
Columbus Free Press (Publisher)
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Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Central Ohio Green Party meeting [PDF]
, 1985 Members gathered around a table during a meeting of the Central Ohio Green Party, taken for the Columbus Free Press. The group appears to be in a church basement or similar space--a donation box labeled "TLCW Stewardship Box" is visible along the back ...
Columbus Free Press (Publisher)
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The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Columbus AIDS Task Force staff and board members [PDF]
, 1985 Group photograph from the Columbus Free Press Collection showing the Columbus AIDS Task Force staff and board members. Front row, left to right: H. L. Wright III, board vice president; Gloria J. T.
Columbus Free Press (Publisher)
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