Results 181 to 190 of about 25,976,263 (323)

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Efficacy and safety of needle-free injection in patients with type 2 diabetes mellitus undergoing intensive insulin therapy: a randomized controlled trial based on the flash glucose monitoring system. [PDF]

Front Endocrinol (Lausanne)
Wang J, Liu Z, Jiao L, Zhou J, Wang T, Li C, Wang Q, Yuan L, Zhang F, Li G, Zhu Q, Jin S, Zhang L.   +12 more
europepmc   +1 more source

Patterns of EFL Learners’ and Instructor’s Interactions in Asynchronous Group Discussions on Free Writing [PDF]

, 2018
Mohammed Abdullah Alharbi
openalex   +1 more source

Casimir functions of free nilpotent Lie groups of steps three and four [PDF]

, 2020
A. V. Podobryaev
openalex   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source

Effect of Preserved Versus Preservative-Free Artificial Tears on the Corneal Epithelial Thickness Mapping by MS-39 in Dry Eye Patients. [PDF]

J Ophthalmol
Nassar GA, Ashor AR, Hosny M, Alio J, Farag AA.   +4 more
europepmc   +1 more source

PSL(2,C), the exponential and some new free groups [PDF]

, 2015
Daniel Panazzolo
openalex   +1 more source

Algebraic numbers, free group automorphisms and substitutions on the plane

, 2011
P. Arnoux, Maki Furukado, E. Harriss, Shunji Ito   +3 more
semanticscholar   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

The Reconstruction of Cycle-free Partial Orders from their Abstract Automorphism Groups II : Cone Transitive CFPOs [PDF]

, 2015
Robert Barham
openalex   +1 more source