Results 121 to 130 of about 3,284,389 (358)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

The prevalence of behavioral non- communicable diseases risk factors among black Africans in peri-urban community in South Africa

open access: yesClinical Nutrition Open Science
Summary: Background: Non-communicable diseases (NCDs) are a leading cause of mortality in South Africa, with their burden influenced by lifestyle, living conditions, ethnicity, and gender.
Sifundile Zamazulu Maphumulo   +3 more
doaj   +1 more source

Intellectual Property and Intra-Community Trade [PDF]

open access: yes, 1996
This Article will use recently decided intellectual property cases and other recent developments in European Community competition law to critically discuss the European Community\u27s traditional and strict pro-free trade approach in intellectual ...
Reindl, Andreas
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

TAXATION OF PER DIEM. ROMANIAN CURRENT LIABILITIES FOR EMPLOYERS AND EMPLOYEES [PDF]

open access: yesCES Working Papers, 2015
The accession to EU opened new opportunities in the area of transnational services, by using Romanian employees abroad. The general principle of free movement of labor allowed the employers to send their workers in another member states, under the ...
Mihaela TOFAN, Ana Maria BERCU
doaj  

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