Results 151 to 160 of about 9,771,631 (353)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

A hybrid 3d reconstruction/registration algorithm for correction of head motion in emission tomography [PDF]

open access: yes, 2000
Even with head restraint, small head movements can occur during data acquisition for emission tomography, sufficiently large to result in detectable artifacts in the final reconstruction.
Fulton, R.R.   +4 more
core  

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

The prevalence of behavioral non- communicable diseases risk factors among black Africans in peri-urban community in South Africa

open access: yesClinical Nutrition Open Science
Summary: Background: Non-communicable diseases (NCDs) are a leading cause of mortality in South Africa, with their burden influenced by lifestyle, living conditions, ethnicity, and gender.
Sifundile Zamazulu Maphumulo   +3 more
doaj   +1 more source

TAXATION OF PER DIEM. ROMANIAN CURRENT LIABILITIES FOR EMPLOYERS AND EMPLOYEES [PDF]

open access: yesCES Working Papers, 2015
The accession to EU opened new opportunities in the area of transnational services, by using Romanian employees abroad. The general principle of free movement of labor allowed the employers to send their workers in another member states, under the ...
Mihaela TOFAN, Ana Maria BERCU
doaj  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Free Movement for Whom? Gendered Dynamics in the Access to Mobility Infrastructures in West Africa

open access: yesGerman Law Journal
The Economic Community of West African States (“ECOWAS”) has established one of the most comprehensive free movement regimes. By declaring West Africa a borderless region, the organization affirms the right of free movement for all citizens of member ...
Amalie Ravn Weinrich
doaj   +1 more source

Home - About - Disclaimer - Privacy