Results 51 to 60 of about 5,578,766 (311)

How Citizenship Divides: The New Legal Class of Transnational Europeans

open access: yesEuropean Papers, 2020
(Series Information) European Papers - A Journal on Law and Integration, 2019 4(3), 675-694 | Article | (Table of Contents) I. Introduction. - II. The selective nature of Union Citizenship. - III. The right to live in another Member State. - IV.
Gareth Davies
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

Free movement of goods and services in the EU and in Tunisia-EU relations: reality and challenges

open access: yes, 2022
This thesis aims to compare from one hand the free movement of goods and services in the European Union and from the other hand EU relations, regarding the movement of the aforementioned, with Tunisia as a Mediterranean partner.
Yousfi, Mourad
core  

Emerging experimental and computational methods for studying redox‐regulated structural transitions

open access: yesFEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

open access: yesFEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança   +2 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Effects of Great Britain's Exit from the European Union [PDF]

open access: yesOvidius University Annals: Economic Sciences Series, 2017
The exit of the UK from the European Union established by the referendum of 23.06.2016 willproduce important changes in the further development of the European Union.
Amarița Adrian
doaj  

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Evaluating Costs and Benefits of Romanian’s Integration into the European Union [PDF]

open access: yesRomanian Journal of European Affairs, 2004
The study „A Cost-Benefit Assessment of Romania’s Accession to the European Union”, part of the programme Pre-Accession Impact Studies II that was coordinated by the European Institute of Romania, tries to offer a partial image of an evaluation of the ...
Constantin Ciupagea   +5 more
doaj  

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