Results 111 to 120 of about 971,851 (311)

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Developing Competence Based Qualification System in the Nuclear Energy Sector [PDF]

open access: yes, 2016
In a changing world, the EU needs to develop a smart, sustainable and inclusive economy. These three mutually reinforcing priorities should help the Member States deliver high levels of employment, productivity and social cohesion.
CECLAN MIHAIL
core  

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Issues and Prospects on the Movement of Natural Persons and Human Capital Development in the Philippine-American Economic Relations [PDF]

open access: yes, 2006
The United States of America is the top trading partner of the Philippines and also the top destination of highly skilled and professional Filipino workers.
Cortez, Michael Angelo A.   +1 more
core  

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

open access: yesFEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point   +7 more
wiley   +1 more source

Confronting the Competence Conundrum of an EU Directive on Minimum Wages: In Search of a Legal Basis. College of Europe Policy Brief #9.19 December 2019 [PDF]

open access: yes, 2019
> The new European Commission has boldly announced its plans to deliver an EU minimum wage legal measure within the first 100 days in office. > This commendable ambition raises the muchcontested question of competence in this field.
Aranguiz, Ane, Garben, Sacha
core   +1 more source

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

New Labour? The Impact of Migration from Central and Eastern European Countries on the UK Labour Market [PDF]

open access: yes
The UK was one of only three countries that granted free movement of workers to accession nationals following the enlargement of the European Union in May 2004.
Lemos, Sara, Portes, Jonathan
core   +3 more sources

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