Results 241 to 250 of about 1,418,478 (304)

How phagocytic cells kill bacteria: Lessons from a professional killer

FEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Structure of the (Total) Transformation Monoids Under Rank N Generators. [PDF]

F1000Res
M Sulaiman H, Al-Aadhami A.
europepmc   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Technological, Functional, and Sensory Evaluation of Sorghum Extruded Snacks Enriched with Chokeberry Pomace. [PDF]

Foods
Janić Hajnal E, Pezo L, Banjac V, Škrobot D, Travičić V, Filipčev B, Perduh B, Kos J, Šimurina O, Cvetković B.   +9 more
europepmc   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

FEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Structural basis for uracil removal from DNA by human SMUG1. [PDF]

Nat Commun
Ludäscher JM, Scaletti Hutchinson E, Vila-Julià G, Jemth AS, Shahid S, Wiita E, Cabeza de Vaca I, Pach S, Gajdos L, Aggarwal S, Walse E, Mortusewicz O, Helleday T, Carlsson J, Stenmark P.   +14 more
europepmc   +1 more source

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Editorial: Human factors and cognitive ergonomics in advanced industrial human-robot interaction

Frontiers in Robotics and AI
Erik Billing, Federico Fraboni, Luca Gualtieri, Patricia Helen Rosen, Peter Thorvald   +4 more
doaj   +1 more source

Early-stage drug discovery in a new-generation ultrahigh-throughput mass spectrometry platform. [PDF]

Proc Natl Acad Sci U S A
Morato NM, Feng Y, Chen K, Huang KH, Owen A, Caruso JV, Yang B, Kulathunga SC, Mesecar AD, Klumpp-Thomas C, Radujevic A, Godfrey AG, Gardner S, Rudnicki DD, Galbraith M, Gloeckner A, Hajdu C, Pringle SD, Morris M, Balog J, Cooks RG.   +20 more
europepmc   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source