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Free Radical Scavenging by Ethanol Extract of Propolis
International Journal of Radiation Biology, 1990The free radical scavenging ability of an ethanolic extract of propolis (EEP) was demonstrated by electron spin resonance spectroscopy, when 2,2-diphenyl-1-picrylhydrazyl (DPPH) was treated with increasing concentrations of EEP. It was shown that the DPPH signal intensity was inversely related to the EEP concentration and to the reaction time.
Wojciech Król +5 more
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Suppression of the formation of megamitochondria by scavengers for free radicals
Molecular Aspects of Medicine, 1997In the present study we have attempted to suppress the formation of megamitochondria by scavengers for free radicals since conditions for the formation of megamitochondria are often intimately related to the generation of free radicals. We employed three different experimental conditions to induce megamitochondria in the liver: ethanol, hydrazine and ...
Jerzy Antosiewicz +5 more
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INHIBITION OF DITHRANOL INFLAMMATION BY FREE-RADICAL SCAVENGERS
The Lancet, 1984Dithranol (anthralin) inflammation of forearm skin was completely inhibited by various scavengers of free radicals of the oxygen species. It is concluded that dithranol inflammation is initiated by formation of free radicals; these may act through lipid peroxidation and production of inflammatory endoperoxides or by a more direct mechanism.
Clifford M. Lawrence +2 more
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Probucol, a superoxide free radical scavenger in vitro
Atherosclerosis, 1991Free radical (FR) mediated oxidation of low density lipoproteins (LDL) has been implicated in atherogenesis. Probucol is a lipid lowering agent with antioxidant properties which may protect the LDL from FR mediated damage. The specific mechanism by which probucol acts as an antioxidant has not previously been reported.
Bridges, A.B. +2 more
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The Role of Free Radical Scavengers in Reperfusion
1988Recently, oxygen radicals have been implicated in the pathogenesis of many diseases. This is reflected in the many conferences devoted to this topic and in the numerous books that cover the field in a systematic manner [1, 2, 3, 4, 5, 6]. Much attention is currently focused on a role for oxygen radicals in heart and blood-vessel abnormalities and in ...
Claudio Ceconi +5 more
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Prevention of testicular damage by free-radical scavengers
Urology, 1997The role of free radicals as mediators of ischemic injury to the testicle has been the subject of much investigation. We studied whether the testicular damage induced in the rat by cadmium chloride (CdCl2) can be prevented by administration of free-radical scavengers.Sprague-Dawley rats (n = 45) were divided into 9 groups as follows: a negative control
Kevin R. Loughlin +5 more
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Free Radical Scavengers and Spin Traps
1997This chapter explores the role of free radical scavengers and spin trapping agents in preventing cell death. Reactive oxygen species (ROS) can be generated in ischemic/reperfused tissues by a number of pathways. Electron transport associated with mitochondrial membranes is a major contributor to ROS formation in the normoxic brain.
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Carbon Nanotubes as Free-Radical Scavengers
The Journal of Physical Chemistry C, 2008Density functional theory calculations have been used to model the potential ability of single-walled carbon nanotubes (SWCNT) to act as free-radical scavengers. The reactions of a (5,5) SWCNT fragment with six different radicals have been studied, and for hydroxyl radical, which is the most reactive and dangerous from all of the studied set, up to ...
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Studies on the activity of bepridil as a scavenger of free radicals
Biochemical Pharmacology, 1990Bepridil, a calcium antagonist with anti-anginal, anti-ischemic, and anti-arrhythmic properties was assessed for its ability to scavenge free radicals. Bepridil reduced the stable free radical 1,1-diphenyl-2-picrylhydrazil (DPPH) in the molar ratio 2:1 and, in this respect, was as active as the reference anti-oxidants hydroquinone and alpha-tocopherol.
Christine Bromont +3 more
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Antioxidants and free radical scavengers
1994An antioxidant may be defined as any substance that can delay or prevent the oxidation of a substrate when it is present in small amounts relative to the amount of the substrate. Antioxidant protection consists of three sequential levels of defensive activity. The first level of defense—which is largely enzymatic—involves enzymes, the activity of which
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