Results 251 to 260 of about 2,007,881 (314)

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Placing anurans in water can improve photo-based individual identification. [PDF]

PLoS One
Nemesházi E, Mikó Z, Ujhegyi N, Kásler A, Lehofer N, Bókony V.   +5 more
europepmc   +1 more source

Free chemistry software online

Materials Today, 2003
openaire   +1 more source

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

FEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn, Barbara Seroka, Ryszard Lazny, Zenon Lotowski, Thore Rohwerder   +4 more
wiley   +1 more source

Personalized p-THYROSIM model for thyroid hormone dynamics, hypothyroidism treatment & implementation in an iOS version for wide distribution. [PDF]

Front Endocrinol (Lausanne)
DiStefano J, Reid K, Ghabra K, Chen R, Narayanan SS.   +4 more
europepmc   +1 more source

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

FEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth, Moritz Koch, Le‐Han Rössner, Johanna Eichhorn, Denys Pogoryelov, Matthias P. Mayer, Jude M. Przyborski   +6 more
wiley   +1 more source

Endoscopic ultrasound-free lumen apposing metal stent recanalization of a complete ileal J-pouch stenosis restoring intestinal continuity. [PDF]

Endoscopy
Graceffa P, Sparacino A, Bracciamà E, Cartabellotta F, Callari C, Granata A.   +5 more
europepmc   +1 more source

Low spatial mobility of associated microbes along the hyphae limits organic nitrogen utilization in the arbuscular mycorrhizal hyphosphere. [PDF]

Front Plant Sci
Vieira CK, Rozmoš M, Kotianová M, Hršelová H, Bukovská P, Jansa J.   +5 more
europepmc   +1 more source

Development and validation of an AI-based lung lobe auto-contouring tool using radiation therapy planning free-breathing images. [PDF]

Rep Pract Oncol Radiother
Ciaccio P, Lombardo J, Fuquay A, Pahlavian S, Grimm R, Kang J, Choi W, Sullivan P, Vinogradskiy Y.   +8 more
europepmc   +1 more source

Social justice and an Information Democracy with Free and Open Source software

, 2011
C. Sean Burns
openalex   +1 more source