Results 51 to 60 of about 112,460 (304)
Voices in Bioethics, 2020 I. Introduction In Sorrell v. IMS Health, the Supreme Court struck down a Vermont regulation requiring pharmacies to obtain prescriber consent to release prescriber-identifying information[1] to data miners for marketing research purposes.
Anne Zimmerman
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Free Speech, Freedom of the Press, and the Tapestry of Lies
Nordicum-Mediterraneum, 2015 This paper comprises the text of the invited lecture presented at the international conference, "Tjáningarfrelsi og félagsleg ábyrgð - Kenningar og útfærsla" (Freedom of Expression and Social Responsibility – Theory and Practice), held at the University ...
Mikael M. Karlsson
doaj
FEBS Open Bio, EarlyView.What factors make for an effective digital learning tool in Higher Education? This systematic review identifies elements of a digital tool that published examples reveal to be features of an engaging and impactful digital tool. A systematic literature search yielded 25 research papers for analysis.
Akmal Arzeman +4 more
wiley +1 more source
The Lives of Others: Unauthorized Depictions of Public Figures in U.S. Film and TV Drama
International Journal of Communication, 2023 This article examines the unauthorized depiction of public figures in contemporary U.S. film and TV from a legal perspective, particularly the conflict between free speech and reputational damage.
Jonathan Stubbs
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Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
FEBS Open Bio, EarlyView.Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Mediating Banal Populism Through Vlogging in the Philippines
International Journal of Communication, 2023 The belligerent us-versus-them divide typical of populism is central to the expression of contemporary politics. Political leaders and their social media entrepreneurs, however, are increasingly embracing nonantagonistic measures to embolden their ...
Jefferson Lyndon D. Ragragio
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FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
STRUCTURAL-SEMANTIC TYPOLOGIZATION OF FREE INDIRECT SPEECH: THE CASE OF MARINA TSVETAEVA’S PROSE
Sovremennye Issledovaniâ Socialʹnyh Problem, 2018 The article is devoted to the topic of someone else’s speech, which remains relevant in modern linguistics. The author studies the way uttered (external) free indirect speech (FIS) (namely, its structural and semantic types) functions in Marina Tsvetaeva’
Olga Pavlovna Puchinina
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