Results 171 to 180 of about 5,227,455 (294)

Molecular recognition between membrane epitopes and nearly free surface silanols explains silica membranolytic activity. [PDF]

Colloids Surf B Biointerfaces, 2022
Pavan C, Sydor MJ, Bellomo C, Leinardi R, Cananà S, Kendall RL, Rebba E, Corno M, Ugliengo P, Mino L, Holian A, Turci F.   +11 more
europepmc   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

Rapid, label-free surface plasmon resonance discrimination between Bothrops and Crotalus venoms using clinical antivenom as the capture reagent. [PDF]

PLoS Negl Trop Dis
Borges ESF, Vasconcelos JS, Melo AA, Loureiro FCCL, Luna KPO, Lima AMN.   +5 more
europepmc   +1 more source

Noise Generation and Acoustic Impact of Free Surface Hydropower Machines: Focus on Water Wheels and Emerging Challenges. [PDF]

Int J Environ Res Public Health, 2021
Quaranta E, Müller G.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Label-free surface sectioning deep ultraviolet tissue imaging in multimodalities. [PDF]

Biomed Opt Express
Chen J, You R, Contreras M, Cai H, Villarreal PP, Vargas G, Hong Z, Liang R.   +7 more
europepmc   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

Predictive value of label-free surface-enhanced Raman spectroscopy for locally advanced gastric cancer following neoadjuvant chemoimmunotherapy. [PDF]

Front Immunol
Wang X, Shi B, Jiang J, Wang W, Wang K, Zhang L, Yuan F, Yao W, Zhang H.   +8 more
europepmc   +1 more source

Implementation of lattice Boltzmann free-surface and shallow water models and their two-way coupling. [PDF]

MethodsX, 2021
Thorimbert Y, Chopard B, Lätt J.
europepmc   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source