Results 171 to 180 of about 3,951,122 (311)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Longer disease progression milestone-free time in people with amyotrophic lateral sclerosis treated versus not treated with intravenous edaravone: results from an administrative claims analysis. [PDF]

J Comp Eff Res
Berry JD, Hagan M, Zhang J, Liu Y, Ciepielewska M.   +4 more
europepmc   +1 more source

Leisure and Procrastination, a Quest for Autonomy in Free Time Investments: Task Avoidance or Accomplishment? [PDF]

Front Psychol, 2019
Pestana JV, Codina N, Valenzuela R.
europepmc   +1 more source

Effect of Dexmedetomidine Added to Standard Care on Ventilator-Free Time in Patients With Agitated Delirium [PDF]

, 2016
Michael C. Reade, Glenn M. Eastwood, Rinaldo Bellomo, Michael Bailey, Andrew D. Bersten, Benjamin Cheung, Andrew Davies, Anthony Delaney, Angaj Ghosh, Frank van Haren, Nerina Harley, David Knight, Shay McGuiness, John Mulder, Steve O’Donoghue, Nicholas Simpson, Paul J. Young   +16 more
openalex   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

PostFocus: automated selective post-acquisition high-throughput focus restoration using diffusion model for label-free time-lapse microscopy. [PDF]

Bioinformatics
Wu KL, Montalvo MJ, Menon PS, Roysam B, Varadarajan N.   +4 more
europepmc   +1 more source

Pedagogy of free time: social and philosophical analysis

, 2017
Grygorii Khoruzhyi
openalex   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Effects of Physical Exercises and Verbal Stimulation on the Functional Efficiency and Use of Free Time in an Older Population under Institutional Care: A Randomized Controlled Trial. [PDF]

J Clin Med, 2020
Wiśniowska-Szurlej A, Ćwirlej-Sozańska A, Wołoszyn N, Sozański B, Wilmowska-Pietruszyńska A.   +4 more
europepmc   +1 more source

Surprisal analysis characterizes the free energy time course of cancer cells undergoing epithelial-to-mesenchymal transition [PDF]

, 2014
Sohila Zadran, Rameshkumar Arumugam, Harvey Herschman, Michael E. Phelps, R. D. Levine   +4 more
openalex   +1 more source