Results 61 to 70 of about 45,475 (358)

Enhancing Specificity, Precision, Accessibility, Flexibility, and Safety to Overcome Traditional CRISPR/Cas Editing Challenges and Shape Future Innovations

Advanced Science, EarlyView.
CRISPR/Cas9, while transformative, faces challenges in specificity, precision, delivery, accessibility, flexibility, and safety. This review addresses these limitations by highlighting strategies to reduce off‐target effects, exploring HDR‐based and alternative editing approaches, and evaluating advanced delivery mechanisms.
Muna Alariqi, Mohamed Ramadan, Lu Yu, Fengjiao Hui, Amjad Hussain, Xiaofeng Zhou, Yu Yu, Xianlong Zhang, Shuangxia Jin   +8 more
wiley   +1 more source

A rare complication of maxillary third molar extraction

Journal of Pharmacy and Bioallied Sciences
The removal of tuberosity post extraction of the maxillary third molar is a very rare complication and there has not been ample discussion in the literature. Forceful extraction of a maxillary third molar can lead to soft and hard tissue loss.
Gursimrat Kaur Brar, Vanita Keshav, Surender Pal Singh Sodhi, Ujjwal Chawla, Asmita Sodhi   +4 more
doaj   +1 more source

Surgical Management of Bulky Mediastinal Metastases in Follicular Thyroid Carcinoma

Oman Medical Journal, 2016
Follicular thyroid adenoma and carcinoma are very common. Benign and malignant lesions are usually indistinguishable from cytology alone and often require confirmatory resection.
Zainal Adwin, Ayub Nur, Shahrun Suhaimi, Ramzisham Rahman   +3 more
doaj   +1 more source

Free thoracodorsal artery polyfoliate perforator flaps for repairing multiple soft tissue defects in the hand

BMC Surgery, 2021
Background Hand injury is commonly associated with multiple soft tissue defects. Polyfoliate flaps grafting is the optimal approach for multiple wounds.The feasibility of clinical using of free thoracodorsal artery polyfoliate perforator flaps for ...
Wenquan Ding, Jianbo Xue, Yingling Zhou, Lingfeng He, Xiaofeng Wang   +4 more
doaj   +1 more source

Coactosin‐Like Protein Reduces Prostaglandin D2 Production in Alveolar Macrophages and Alleviates Allergic Airway Inflammation

Advanced Science, EarlyView.
Coactosin‐like protein inhibits prostaglandin D₂ (PGD2) secretion by modulating alveolar macrophage polarization, thereby suppressing activation of the PGD2 receptor CRTH2 in Th2‐associated immune cells and alleviating allergic airway inflammation.
Li‐Long Pan, Zhengnan Ren, Binbin Li, Wenjie Liang, Yang Luo, Qin Yang, He Liu, Xiaoliang Dong, Haizhi Tian, Huimin Zou, Bengt Samuelsson, Olof Rådmark, Jia Sun   +12 more
wiley   +1 more source

Fasciocutaneous Free Tissue Transfer in Limb Salvage: Prior Flap as a Split-thickness Skin Graft Donor Site

Plastic and Reconstructive Surgery, Global Open, 2023
Summary:. Free flap surgery for limb salvage has become the surgical standard for reconstruction of bone and soft tissue with success rates and flap survivals of 94%–95%. The soft tissue defect dictates the technique of coverage.
Dominik Kaiser, MD, Lawrence Scott Levin, MD   +1 more
doaj   +1 more source

A Novel Cranial Bone Transport Technique Repairs Skull Defect and Minimizes Brain Injury Outcome in Traumatic Brain Injury Rats

Advanced Science, EarlyView.
This study introduces a novel, safe, and effective surgical technique: Cranial bone transport (CBT) to improve traumatic brain injury (TBI) outcomes in rats. CBT significantly accelerated skull defect bone repair in addition to its promoting effects on neurological function recovery. This work provides an alternative therapy for patients suffering from
Shanshan Bai, Xuan Lu, Xu Yan, Han Su, Yuejun Lin, Zhaowei Jiang, Zhixian Zong, Haixing Wang, Leo Yik Chun Yan, Xiaoting Zhang, Ming Wang, Zhengmeng Yang, Jiakang Jin, Yaofeng Wang, Wayne Yuk‐Wai Lee, Xiaohua Jiang, Ho Ko, Lu Feng, Micky D. Tortorella, Sien Lin, Gang Li   +20 more
wiley   +1 more source

Bioinspired Intelligent Soft Robotics: From Multidisciplinary Integration to Next‐Generation Intelligence

Advanced Science, EarlyView.
Soft robotics, featuring intrinsic compliance and biomimetic adaptability, emerges as transformative in next‐generation intelligent systems. This review outlines how advancements in four foundational domains—actuation, materials, manufacturing, and control—drive the evolution of bioinspired intelligent soft robotics, poised to redefine the boundaries ...
Xiaopeng Wang, Ruilai Wei, Zhongming Chen, Hao Pang, Haotian Li, Yang Yang, Qilin Hua, Guozhen Shen   +7 more
wiley   +1 more source

Use of Acellular Dermal Matrix to Prevent Recurrence of Radioulnar Heterotopic Ossification. [PDF]

, 2019
Radioulnar heterotopic ossification is a rare occurrence found in approximately 2% of all forearm injuries. Treatment is complicated by relatively high recurrence rates.
Bakhshi, Breuing, Dohn, Ellis, Failla, Fernandez, Friedrich, Joice, Jupiter, Lytle, Maempel, Moyer, Pakos, Sonderegger, Vavken, Vince, Yong-Hing   +16 more
core   +1 more source

Treatment of patients with traumatic hand defects in Krasnodar region

Инновационная медицина Кубани, 2019
Traumatic defects of hand tissues require mostly plasty covering with vascularised flaps. There are a great number of various variants with tissue complexes applied for hand reconstruction. In the present study we demonstrate our clinical experience with
A. M. Aristov, A. A. Afaunov, S. N. Kurinny, A. V. Shevchenko   +3 more
doaj   +2 more sources