Results 61 to 70 of about 6,505,370 (335)
Translating whole‐genome doubling into precision medicine in cancer
Molecular Oncology, EarlyView.Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley +1 more source
The Proliferation of Regional Trade Agreements and Implications for Korea
East Asian Economic Review, 1998 After the WTO system came into effect, the trend of signing new regional trade agreement also lasts. Every county has been positively using regional trade agreements at the strategy level.
In-Kyo Cheong
doaj +1 more source
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Digital trade rulemaking in free trade agreements
, 2023 Langzeitarchivierung durch: Zentral- und Hochschulbibliothek Luzern - zhb:lory_unilu_10_5281_zenodo_12684172 - 2025-07 ...
openaire +2 more sources
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
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Foreign direct investment and free trade agreement
Хабаршысы. Экономика сериясы, 2017 The article examined works on free trade agreement effect on foreign direct investment flows (FDI). Further focusing on Eurasian economic union (EAEU) members’ FDI flows and business climate characteristics including easiness of doing business and ...
Е. Ахметзаки
doaj
Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley +1 more source
Quantitative Assessment of Pakistan and China Free Trade Agreement [PDF]
Pakistan Journal of Commerce and Social Sciences, 2017 The purpose of this paper is to assess the economic impact of tariff eliminations under free trade agreement (FTA) of Pakistan and China on various macroeconomic and trade variables.
Ch. Mazhar Hussain (Corresponding author)
doaj
East Asian Economic Review, 2000 The purpose of this paper is to analyze whether the formation of an FTA will converge or diverge the income levels of its member countries. Although similar former studies predicted, to a certain degree, the possibility of economic convergence among FTA ...
Chan-Hyun Sohn , Hyo-Sung Yim
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Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
Aging and Cancer, EarlyView.This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source