Results 41 to 50 of about 5,100,903 (262)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

THE INTEGRATION MODEL ASEAN+1: THE MAIN NORMS OF AGREEMENTS AND EFFECT ON FOREIGN ECONOMIC TIES

open access: yesVestnik RUDN. International Relations, 2017
The aim of this research is a comparative analysis of the provisions of free trade agreements signed by ASEAN with dialogue countries and the East Asia Summit partners - China, Japan, the Republic of Korea, India, Australia and New Zealand.
Г М Костюнина
doaj   +1 more source

NAPRT loss promotes lung tumor initiation and growth through AKT signaling independently of NAD+ biosynthesis

open access: yesMolecular Oncology, EarlyView.
Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh   +11 more
wiley   +1 more source

El dilema chino: estrategias de desarrollo económico emprendidas por Estados pequeños en Sudamérica

open access: yesColombia Internacional, 2012
The three most prominent trends in South America in the 2000s have been: 1) the rapid expansion of trade and borrowing ties with China; 2) the collapse of both regional and multilateral trade negotiating venues since 2006; and, 3) the quick recovery of ...
Carol Wise
doaj  

The Southern African Development Community Trade Legal Instruments Compliance with Certain Criteria of GATT Article XXIV [PDF]

open access: yesPotchefstroom Electronic Law Journal, 2011
Article XXIV of the General Agreement on Tariffs and Trade (GATT) lays down the legal principles with which regional trade agreements have to conform.
A Saurombe
doaj  

THE IMPACT OF FREE TRADE AGREEMENTS ON THE REPUBLIC OF MOLDOVA’S EXTERNAL TRADE USING A STRUCTURAL GRAVITY MODEL [PDF]

open access: yesEconomica
This paper evaluates the impact of Free Trade Agreements (FTAs) on the Republic of Moldova’s external trade using a structural gravity model, by employing bilateral trade data from 2001 to 2024.
Grigore BUTUCEA
doaj   +1 more source

Optimizing photoexcitation conditions for time‐resolved X‐ray solution scattering experiments

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering (TR‐XSS) is a powerful technique to visualize how proteins change their structure in real time after light activation. Selecting the right laser photoexcitation conditions—fluence, excitation geometry, and sample refresh rate—is critical to maximize the experimental signal while avoiding unwanted side effects ...
Matteo Levantino
wiley   +1 more source

Geographical indications, food safety, and sustainability: conflicts and synergies

open access: yesBio-based and Applied Economics, 2016
This paper examines the legal and policy relationships amongst international standards for GIs, food safety requirements, and voluntary claims related to a food’s attributes.
David Wirth
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

An examining factors influencing international export and import relationships in context of Vietnam’s free trade agreements

open access: yesJurnal Ekonomi & Studi Pembangunan
Vietnam's trade balance was positive with the United States, the Netherlands, Hong Kong, the United Kingdom, the United Arab Emirates, and Austria. However, it was negative in several countries, including South Korea, China, Taiwan, Thailand, Singapore ...
Le Thi Thanh Ha   +2 more
doaj   +1 more source

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