Results 1 to 10 of about 988,366 (311)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Baseline clinical and biochemical profiles of type 2 diabetes patients enrolled in a lifestyle management program in India, a cross-sectional study

Scientific Reports
Assessing the clinical and biochemical profiles of patients with type-2 diabetes (T2D) is vital for understanding the disease characteristics and improving disease management.
Pramod Tripathi, Nidhi Kadam, Thejas Kathrikolly, Diptika Tiwari, Anagha Vyawahare, Baby Sharma, Malhar Ganla, Banshi Saboo   +7 more
doaj   +1 more source

Commentary by Juliet Cohen:

Torture, 2020
This is a response to the article debating what are the ethics of providing medico-legal reports for a victim of torture who may also be a perpetrator.
Juliet Cohen
doaj   +1 more source

Agency-freedom and option-freedom

Journal of Theoretical Politics, 2003
The recent debates about the nature of social freedom, understood in a broadly negative way, have generated three main views of the topic: these represent freedom respectively as non-limitation, non-interference and non-domination. The participants in these debates often go different ways, however, because they address different topics under common ...
openaire   +2 more sources

ACADEMIC FREEDOM [PDF]

Science, 1913
n ...
Leffmann, H., Creighton, J. E.
openaire   +3 more sources

The crystal structure of the Borrelia burgdorferi nicotinamidase BBE22 resolves a long‐standing annotation error

FEBS Open Bio, EarlyView.
The crystal structure of Borrelia burgdorferi nicotinamidase (PncA/BBE22) reveals the correct full‐length protein initiated from a non‐canonical AUU start codon. The structure validates previous biochemical findings and resolves a long‐standing annotation error, demonstrating that the truncated database sequence is structurally incompatible with the ...
Kalvis Brangulis
wiley   +1 more source

Into the headwinds: key emotional intelligence capacities that predict women's workplace wellbeing across job roles

Frontiers in Psychology
IntroductionDespite decades of organizational investment, women's advancement and workplace wellbeing remain at risk. The emotional intelligence (EQ) capacities that support both have not been examined across job roles at scale.
Patricia E. Freedman, Ilaria Iseppato, Daniel Y. Choi, Joshua M. Freedman   +3 more
doaj   +1 more source

Multidimensional Profiling of MRI‐Negative Temporal Lobe Epilepsy Uncovers Distinct Phenotypes

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Although hippocampal sclerosis (TLE‐HS) represents the most frequent cause of temporal lobe epilepsy (TLE), up to 30% of patients show no lesion on visual MRI inspection (TLE‐MRIneg). These cases pose diagnostic and therapeutic challenges and are underrepresented in surgical series.
Alice Ballerini, Alessia Casarini, Niccolò Biagioli, Laura Mirandola, Daniela Ballotta, Paul Summers, Simona Scolastico, Laura Madrassi, Maurilio Genovese, Marcella Malagoli, Gaetano Cantalupo, Giada Giovannini, Matteo Pugnaghi, Niccolò Orlandi, Laura Tassi, Valeria Cuccarini, Domenico Aquino, Elena Tartara, Fulvia Palesi, Giuseppe Didato, Paolo Vitali, the 3TLE Study Group, Roberta Di Giacomo, Fabio Doniselli, Federica Mazzi, Carlo Andrea Galimberti, Claudia A. M. Gandini Wheeler‐Kingshott, Stefano Meletti, Anna Elisabetta Vaudano   +28 more
wiley   +1 more source

Everett E. Dennis: 'La credibilidad es consecuencia de una información verídica'

Cuadernos.info, 1995
El director ejecutivo de The Freedom Forum Media Studies Center, Everette E. Dennis, se ha ido convirtiendo en un personaje familiar para el mundo informativo chileno -tal como lo es desde hace tiempo para el norteamericano.
EVERETTE E DENNIS
doaj   +3 more sources

Microresonator photonic wire bond integration for Kerr-microcomb generation

Scientific Reports
Extremely high-Q microresonators provide an attractive platform for a plethora of photonic applications including optical frequency combs, high-precision metrology, telecommunication, microwave generation, narrow linewidth lasers, and stable frequency ...
Alain Yuji Takabayashi, Nikolay Pavlov, Victoria Rosborough, Galen Hoffman, Lou Kanger, Farzad Mokhtari Koushyar, Taran Huffman, Mike Nelson, Charles Turner, Leif Johansson, Juergen Musolf, Henry Garrett, Thomas Liu, Gordon Morrison, Yanne Chembo, Brian Mattis, Thien-An Nguyen, Mackenzie Van Camp, Steven Eugene Turner, Maxim Karpov, John Jost, Zakary Burkley   +21 more
doaj   +1 more source