Results 71 to 80 of about 628,084 (317)

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐modifying Antirheumatic Drug

open access: yesArthritis Care &Research, Accepted Article.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD) Methods PrismRA incorporated 19 gene expression features and 4 clinical features to assess a patient's likelihood of ...
Fenglong Xie   +3 more
wiley   +1 more source

Hopfield Neural Networks for Online Constrained Parameter Estimation With Time‐Varying Dynamics and Disturbances

open access: yesInternational Journal of Adaptive Control and Signal Processing, EarlyView.
This paper proposes two projector‐based Hopfield neural network (HNN) estimators for online, constrained parameter estimation under time‐varying data, additive disturbances, and slowly drifting physical parameters. The first is a constraint‐aware HNN that enforces linear equalities and inequalities (via slack neurons) and continuously tracks the ...
Miguel Pedro Silva
wiley   +1 more source

Adaptable Tile‐Based Pneumatic Origami through Structurally Coupled Localized Actuation

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents tile‐based pneumatic origami structures with rigid tiles and flexible fabric creases, achieving adaptable properties including morphing shape, selective multistability, and tunable stiffness. Independently pressurized folding bladders at each crease enable structurally coupled localized actuation of origami structures.
Tiantian Li, Jonathan Luntz, Diann Brei
wiley   +1 more source

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

open access: yesAdvanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel   +3 more
wiley   +1 more source

Investigating the Effects of Build Height on Mechanical Behavior of Large‐Scale Laser Wire Directed Energy Deposited Nickel Titanium Alloy

open access: yesAdvanced Engineering Materials, EarlyView.
Laser wire directed energy deposition process was leveraged to fabricate large scale NiTi alloy wall. Evaluation of build‐height‐dependent tribo‐mechanical properties revealed significant differences in location specific sample characteristics. The middle region achieved optimal performance (superior wear resistance, balanced strength‐ductility ...
Hyunsuk Choi   +5 more
wiley   +1 more source

Tracking Religious Freedom Violations with the Violent Incidents Database: A Methodological Approach and Comparative Analysis

open access: yesData
Measuring and comparing religious freedom across countries and over time requires reliable and valid data sources. Existing religious freedom datasets are either based on the coding of qualitative data (such as the Religion and State Project or the Pew ...
Dennis P. Petri   +2 more
doaj   +1 more source

An application of a pattern-mixture model with multiple imputation for the analysis of longitudinal trials with protocol deviations

open access: yesBMC Medical Research Methodology, 2019
Background The benefit of a given treatment can be evaluated via a randomized clinical trial design. However, protocol deviations may severely compromise treatment effect since such deviations often lead to missing values.
Abdul-Karim Iddrisu, Freedom Gumedze
doaj   +1 more source

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