Results 61 to 70 of about 579,988 (303)

Editor's Note: Five Years of Freedom of Information Research

open access: yesThe Journal of Civic Information
The Journal of Civic Information celebrates five years of publishing research about the ability for people to get the information they need to self govern. This editor's note lays out the genesis of the journal, its mission, and top-read articles.
David Cuillier
doaj   +3 more sources

Thalamo‐Lesional Connectivity Signatures of Bilateral Tonic–Clonic Seizures in Focal Cortical Dysplasia‐Related Epilepsy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Focal cortical dysplasia (FCD) is the most common etiology of drug‐resistant epilepsy in children. Focal to bilateral tonic–clonic seizures (FBTCS) mark a high risk of drug‐resistant epilepsy and involve thalamocortical circuitry in their generation and propagation.
Hua Xie   +8 more
wiley   +1 more source

The impact of economic freedom on foreign direct investment: a study of selected Southeast Asian economies [PDF]

open access: yesJournal of Economics and Development
Purpose – This study investigates the impact of economic freedom and its components, including business freedom, trade freedom, investment freedom, financial freedom and monetary freedom, on foreign direct investment net inflows (FDI net inflows). Design/
Buu Kiem Dang, Minh Duc Trinh
doaj   +1 more source

Dimensions of Academic Freedom in Research

open access: yesExperimental Biology and Medicine, 1994
We most often think of academic freedom in terms of the subject and content of lectures and class materials. When controversies arise concerning research, the issues usually concern political correctness or allegations of bias arising either from the sponsorship of the work or from an interest by the researcher in the outcome.
openaire   +2 more sources

Use of a Molecular Signature Response Classifier to Inform Treatment Selection Improves Clinical Disease Activity Among Patients with Rheumatoid Arthritis Initiating a Biologic or Targeted Synthetic Disease‐Modifying Antirheumatic Drug

open access: yesArthritis Care &Research, EarlyView.
Objective We assessed the effectiveness of PrismRA to improve clinical outcomes among patients with rheumatoid arthritis (RA) initiating treatment with a biologic or targeted synthetic disease‐modifying antirheumatic drug (b/tsDMARD). Methods PrismRA incorporated 19 gene expression features and four clinical features to assess a patient's likelihood of
Fenglong Xie   +3 more
wiley   +1 more source

Clinical Significance of Therapeutic Drug Level Monitoring for Mycophenolate in Patients With Extrarenal Systemic Lupus Erythematosus—A Systematic Review and Meta‐Analysis

open access: yesArthritis Care &Research, EarlyView.
Objective Clinical response to mycophenolic acid (MPA) is highly heterogeneous; thus, therapeutic drug level monitoring (TDM) may help improve treatment efficacy. This systematic review and meta‐analysis examined therapeutic ranges for MPA levels associated with better outcomes and safety in patients with systemic lupus erythematosus (SLE ...
Zahraa Qamhieh   +5 more
wiley   +1 more source

Freedom of speech in a therapeutic age

open access: yes, 2017
Roy Harris (2009) and Adrian Pablé (2012) have argued that integrationists, in their philosophy and in their linguistics, have a Socratic approach to freedom of speech that sees vigorous and robust debate as the foundational freedom.
Dennis Hayes, Hayes, Dennis
core   +1 more source

Contradicting Political Dynamics: Democratic Backsliding in Hungary and the Role of the EU

open access: yesPerspective Politice, 2019
Two years ago we started to investigate the ever-widening grey zone between liberal democracy and dictatorship, and applied the findings of the scholarship on hybrid regimes to the characteristics of the Orbán regime in Hungary.1 In this article we ...
András BOZÓKI, Dániel HEGEDUS
doaj  

High Health Care Utilization Preceding Diagnosis With Juvenile Idiopathic Arthritis

open access: yesArthritis Care &Research, EarlyView.
Objective Although early diagnosis improves long‐term outcomes, patients with juvenile idiopathic arthritis (JIA) often experience prolonged, circuitous paths to diagnosis. To inform diagnostic improvement, we sought to characterize health care utilization in the year preceding diagnosis. Methods We identified 10,021 patients with an incident diagnosis
Anna Costello   +5 more
wiley   +1 more source

Cumulative Social Disadvantage and Disease Activity in Juvenile Idiopathic Arthritis: A Childhood Arthritis and Rheumatology Research Alliance Registry Study

open access: yesArthritis Care &Research, EarlyView.
Objective Social determinants of health (SDOH) contribute to juvenile idiopathic arthritis (JIA) disparities, but most studies have assessed SDOH independently rather than cumulatively across individual, family, and neighborhood levels. Using a socioecological framework, we investigated the relationship among cumulative social disadvantage ...
William Daniel Soulsby   +448 more
wiley   +1 more source

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