Results 81 to 90 of about 22,508 (244)

Fallstricke bei Freelance-Verträgen

open access: yes, 2016
Der Einsatz von freien Mitarbeitenden wird immer beliebter. Doch Freelance-Arbeitsverhältnisse bergen aus arbeits- und sozialversicherungsrechtlicher Sicht diverse Risiken.
Slavik, Eva
core   +2 more sources

Venture Labor| Venture Labor and Media Work: The Canary Has Flown

open access: yesInternational Journal of Communication, 2017
The essays in this series provide valuable insights and commentaries on Neff’s Venture Labor. They show both the gains and losses and the winners and losers as work is transformed by the Internet and social media apps.
Paul M. Hirsch
doaj  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Freelance Business

open access: yes, 2021
The thesis deals with a freelance business. The main goal of the thesis is to identify the pros and cons of a freelancers business and to present the current state of freelancers in the Czech Republic.
KORČÁKOVÁ, Kateřina
core  

Success Factors in Leveraging Freelance Marketplaces in Software Development Projects

open access: yes, 2013
The purpose of this research is to explore project success factors and freelance marketplace characteristics that are critical to the success of software development projects on freelance marketplaces, while identifying important metrics to measure the ...
Walter, Alexandre
core   +2 more sources

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Personality Traits of Freelancers Working Remotely

open access: yesВестник Московского университета. Серия 14: Психология
Background. Remote work has been gaining popularity for a long time. With the outbreak of the COVID-19 pandemic, remote work has become a necessity for many people.
Olga N. Rodina , Pavel N. Prudkov
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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