Results 131 to 140 of about 1,305 (252)

Long‐term developmental outcome in infantile epileptic spasms syndrome after high‐dose prednisolone and vigabatrin treatment

open access: yesEpilepsia Open, EarlyView.
Abstract Objective To evaluate long‐term developmental outcomes and identify independent predictors of favorable developmental outcomes at 3 years of age in children with infantile epileptic spasms syndrome (IESS) treated with a standardized stepwise vigabatrin and high‐dose prednisolone protocol.
Soyoung Jang   +5 more
wiley   +1 more source

Effectiveness and safety of cannabidiol in adult patients with epilepsy: A multicenter, retrospective study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Cannabidiol (CBD) has demonstrated promising effectiveness and tolerability as adjunctive treatment in patients with severe childhood epilepsies. This study investigated the effectiveness and tolerability of CBD in adults with a history of Dravet syndrome (DS), Lennox–Gastaut syndrome (LGS), or tuberous sclerosis complex (TSC ...
Sara Sánchez‐Gamino   +7 more
wiley   +1 more source

Transcutaneous auricular vagus nerve stimulation in drug‐resistant epilepsy: A randomized, sham‐controlled crossover trial with exploratory EEG and MRI response phenotyping

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Transcutaneous auricular vagus nerve stimulation (taVNS) is a noninvasive neuromodulation strategy for drug‐resistant epilepsy, but clinical response is heterogeneous. We examined whether electroencephalographic (EEG) and structural magnetic resonance imaging (MRI) phenotypes were associated with active‐specific clinical benefit from
Sung Jun Hong   +6 more
wiley   +1 more source

Fenfluramine in Rett syndrome: A multidimensional clinical study

open access: yesEpilepsia Open, EarlyView.
Abstract Objective Rett syndrome (RTT) is a severe neurodevelopmental disorder frequently associated with drug‐resistant epilepsy, autonomic dysfunction, respiratory abnormalities, sleep disturbances, and behavioral impairment. Fenfluramine has shown efficacy in developmental and epileptic encephalopathies and may provide broader therapeutic benefits ...
Elena Gonzalez‐Alguacil   +11 more
wiley   +1 more source

COVID-19 advocacy bias in the <i>BMJ</i>: meta-research evaluation. [PDF]

open access: yesBMJ Open Qual
Kepp KP   +3 more
europepmc   +1 more source

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