Results 91 to 100 of about 1,230 (212)

Technology adoption in healthcare: Delphi consensus for the early exploration and agile adoption of emerging healthcare technology conceptual framework

open access: yesBMJ Health & Care Informatics
Objectives In the ever-evolving landscape of healthcare, the integration of digital systems and medical devices is increasingly important for modernising healthcare delivery.
  +18 more
doaj   +1 more source

Predicting seizure freedom in the postpartum period: Findings from the Maternal Outcomes and Neurodevelopmental Effects of Antiepileptic Drugs study

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate whether seizure freedom in pregnancy predicts seizure freedom in the postpartum period in women with epilepsy (WWE). Prior studies have shown that seizure freedom prior to conception strongly predicts seizure freedom during pregnancy.
Emma C. Osterhaus   +7 more
wiley   +1 more source

Feasibility and signal quality of the Minder® implantable continuous EEG monitoring® system compared to 10–20 scalp electrodes over extended monitoring periods

open access: yesEpilepsia, EarlyView.
Abstract Objective To evaluate the signal quality of the Minder implantable continuous EEG monitoring (iCEM) system compared to traditional scalp EEG in the context of long‐term, continuous monitoring in individuals with epilepsy. Methods Twenty‐six patients implanted with the Minder iCEM system (November 2019 to July 2023) underwent 7‐day video‐EEG co‐
Taneeta Mindy Ganguly   +15 more
wiley   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

open access: yesEpilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen   +15 more
wiley   +1 more source

Responsive stimulation of the thalamus for idiopathic generalized epilepsy: Results of the randomized controlled NAUTILUS trial through 18 months

open access: yesEpilepsia, EarlyView.
Abstract Objective This study was undertaken to evaluate the safety and effectiveness of responsive thalamic stimulation as adjunctive therapy for drug‐resistant idiopathic generalized epilepsy (IGE) with generalized tonic–clonic seizures (GTCSs). Methods NAUTILUS is a prospective, multicenter, single‐blind, randomized sham‐controlled pivotal trial ...
Utku Uysal   +47 more
wiley   +1 more source

Tonic–clonic seizures captured during ambulatory video‐EEG are frequently unreported

open access: yesEpilepsia, EarlyView.
Abstract Objective Tonic–clonic seizures (TCSs) are widely regarded as clinically obvious, yet seizure counts used for treatment decisions and risk counseling often rely on patient or caregiver diaries. We sought to quantify the frequency of unreported TCSs during prolonged ambulatory video‐EEG (vEEG) monitoring and examined associations with ...
Ewan S. Nurse   +3 more
wiley   +1 more source

Gamma suppression correlates with thalamic stimulation therapeutic response in intractable epilepsy

open access: yesEpilepsia, EarlyView.
Abstract Objective In patients with drug‐resistant epilepsy who undergo anterior nucleus of the thalamus (ANT) deep brain stimulation (DBS), efficacy is assessed months after therapy initiation and clinicians have no guidance when choosing stimulation parameters due to the lack of real‐time biomarkers.
Zachary T. Sanger   +10 more
wiley   +1 more source

Intermittent fasting with medium‐chain triglycerides in drug‐resistant epilepsy: A pilot crossover trial

open access: yesEpilepsia, EarlyView.
Abstract Objective Ketogenic dietary therapies can reduce seizure frequency in drug‐resistant epilepsy, but adherence to the classical ketogenic diet is often poor. Intermittent fasting supplemented with medium‐chain triglycerides (MCTs) may offer a more feasible and less restrictive alternative.
Wiebke Hahn   +11 more
wiley   +1 more source

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