Results 111 to 120 of about 23,865 (283)
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Biographical meanings of work: the case of a Polish freelancer
Przeglad Socjologii Jakosciowej, 2017 The sociological analyses of contemporary society mostly emphasize its liquid and flexible character, which provides new opportunities, but also threats, on both the macro and individual level. The incoherence of the present times could, however, also be
Karol Haratyk +2 more
doaj +1 more source
Aspects of Non-Standard Employment in Europe [PDF]
, 2017 [Excerpt] This report investigates recent developments in non-standard employment in the European Union. While the overall policy context is ‘social protection for all’, it does not focus exclusively on social protection.
Eurofound
core +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
Income and Distribution Analysis with the Taxpayer-Panel - New Prospects and First Results for Self-Employed, as Freelancers and Entrepeneurs, and Employees as Well as for High Incomes [PDF]
This contribution analyzes the personal income distribution with the actual microdata of the German Income Tax Statistics and focus on top incomes for important labour market groups: the self-employed (as freelancers and entrepreneurs) and employees. New
Merz, Joachim, Zwick, Markus
core +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Income Taxes and Entrepreneurial Choice: Empirical Evidence from Germany [PDF]
Entrepreneurial activity is often regarded as an engine for economic growth and job creation. Through tax policy, governments possess a potential lever to influence the decisions of economic agents to start and close small businesses. In Germany, the top
Frank M. Fossen, Viktor Steiner
core
PEMBUATAN FONT BRUSH SCRIPT MENGGUNAKAN ADOBE ILLUSTRATOR, FONTLAB STUDIO DAN ADOBE PHOTOSHOP [PDF]
, 2016 Pembuatan font brush script yang bertujuan untuk mengetahui proses pembuatan font script dari manual kedigital sehingga dapat digunakan semestinya. Font mena brush script dimanfaatkan untuk dapat menambah fariasi font, dapat dipasarkan di market place ...
Kasyful Mena
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source