Results 131 to 140 of about 33,289 (326)
Entgrenzung als allgemeinerer Trend? Mobile Pflege und Arbeit in der Medien- und Kulturindustrie im Vergleich [PDF]
In der deutschsprachigen Arbeits- und Industriesoziologie wird derzeit eine intensive Debatte über die Entgrenzung von Erwerbsarbeit geführt. Hiermit ist gemeint, dass sich die industriegesellschaftlich etablierten Grenzen von Erwerbsarbeit verflüssigen ...
Henninger, Annette, Papouschek, Ulrike
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Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
PEMBUATAN FONT BRUSH SCRIPT MENGGUNAKAN ADOBE ILLUSTRATOR, FONTLAB STUDIO DAN ADOBE PHOTOSHOP [PDF]
Pembuatan font brush script yang bertujuan untuk mengetahui proses pembuatan font script dari manual kedigital sehingga dapat digunakan semestinya. Font mena brush script dimanfaatkan untuk dapat menambah fariasi font, dapat dipasarkan di market place ...
Kasyful Mena
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Laundering Money Online: a review of cybercriminals methods
Money laundering is a critical step in the cyber crime process which is experiencing some changes as hackers and their criminal colleagues continually alter and optimize payment mechanisms.
Richet, Jean-Loup
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Senator Ellis sponsors financial assistance for postsecondary education -- Student events require student input -- Opinion: Sexual deviancy and the Myspace generation -- Employers offer summer employment to UAS students -- Eaglecrests hosts UAS Snow Jam ...
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