Results 231 to 240 of about 23,865 (283)

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

FEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid, Rapasviranda Soiyangsuk, Maneeluck Tanadjindarat, Chayanon Peerapittayamongkol   +3 more
wiley   +1 more source

Perceptions and experiences of patients with endodontic instrument separation-a qualitative study. [PDF]

BMC Oral Health
Liu X, Yuan X, Lv R, Li Y, Xia T, Wang Z, Zhai J, Lv A.   +7 more
europepmc   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Sudanese medical students' satisfaction with online learning and its association with their psychological distress: a cross-sectional study. [PDF]

BMC Med Educ
Ahmed MBM, Ahmed ABM, Gasmalha MEA, Abdalla OZE, Ahmed SHM, Mohammed BAA, Ebrahim RAO, Abdeen MHS, Babiker EOM, Ahmed TAA, Ahmed AAO, Ahmed DSM, Mubashir M, Ahmed SMM.   +13 more
europepmc   +1 more source

Mothers' Self-Worth and Children's Achievements: A Q Methodological Analysis of Perception Types. [PDF]

Behav Sci (Basel)
Lee K, Lee SY, Lee S.
europepmc   +1 more source

Prevalence of depression among diabetic patients and its relationship to diabetes self-care activities, disease profile, and social factors in Khartoum State, Sudan: A cross-sectional study. [PDF]

Medicine (Baltimore)
Emad S, Elawad S, Elawad SOM, M Ahmed AB, Elbadawi MH, Khalid L, Abdalhamed TYM, Sosal W, Haiba AM.   +8 more
europepmc   +1 more source

The effect of an educational intervention based on the PRECEDE Model on anxiety caused by Covid-19 in pregnant mothers. [PDF]

J Educ Health Promot
Jalili Z, Gholizadeh A, Shojaeizadeh D.
europepmc   +1 more source

A Case Report of Giant Congenital Melanocytic Nevus Complicated by Minimal Change Disease, With Genetic Analysis. [PDF]

Clin Case Rep
Yu G, Hu T, Yu T, Zhao Y, Xu X.
europepmc   +1 more source

The impacts of Bolsa Família, Cisterns, and PRONAF on rural women's food practices in Northeast Brazil: a qualitative analysis. [PDF]

Int J Equity Health
Simões ML.
europepmc   +1 more source