Results 141 to 150 of about 234,413 (355)

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

open access: yesFEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke   +4 more
wiley   +1 more source

Compact Personalized Models for Neural Machine Translation

open access: yes, 2018
We propose and compare methods for gradient-based domain adaptation of self-attentive neural machine translation models. We demonstrate that a large proportion of model parameters can be frozen during adaptation with minimal or no reduction in ...
DeNero, John   +2 more
core   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

open access: yesFEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik   +6 more
wiley   +1 more source

Freeze-thawing stool up to four times does not affect bacterial taxa abundance.

open access: green, 2015
Monika A. Gorzelak (781453)   +5 more
openalex   +2 more sources

Drone-based sea ice albedo measurements and photogrammetry during the Arctic freeze-up in the MOSAiC expedition

open access: gold, 2021
Roberta Pirazzini   +4 more
openalex   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Effect of Pooling and Freeze-Thaw Processes on the PRRSV RNA Detection in TOSc Samples

open access: yesVeterinary Sciences
Tonsil oral scrubbing (TOSc) is a simple and practical method recently developed for detecting PRRSV RNA in sows. This study evaluated how pooling and freeze-thaw procedures affect PRRSV RT-rtPCR results in TOSc samples.
Peng Li   +6 more
doaj   +1 more source

AFES Miscellaneous Publication 2010-02 [PDF]

open access: yes, 2010
Research has been conducted since 2001 to assist growers in identifying components of peony field cut flower production and distribution from field selection and planting to post harvest handling and packaging for export.
Hanscom, Janice   +2 more
core  

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