Results 101 to 110 of about 10,630 (263)

Determination of optimal vibration dose to treat Parkinson's disease gait symptoms: A clinical trial

open access: yesClinical Parkinsonism & Related Disorders
Introduction: Most people with Parkinson's disease (PD) will experience gait problems. Previous studies demonstrated improved gait and balance after vibration stimulation was applied to the feet of PD patients.
Ingrid Pretzer-Aboff   +5 more
doaj   +1 more source

Organic Thin‐Film Transistors for Neuromorphic Computing

open access: yesAdvanced Electronic Materials, EarlyView.
Organic thin‐film transistors (OTFTs) are reviewed for neuromorphic computing applications, highlighting their power‐efficient, and biological time‐scale operation. This article surveys OFET and OECT devices, compares them with memristors and CMOS, analyzes how fabrication parameters shape spike‐based metrics, proposes standardized characterization ...
Luke McCarthy   +2 more
wiley   +1 more source

Upper Extremity Freezing and Dyscoordination in Parkinson’s Disease: Effects of Amplitude and Cadence Manipulations

open access: yesParkinson's Disease, 2013
Purpose. Motor freezing, the inability to produce effective movement, is associated with decreasing amplitude, hastening of movement, and poor coordination.
April J. Williams   +4 more
doaj   +1 more source

How Halide Segregation Governs the Ion Density Evolution and Ionic Performance Losses: From Degradation to Recovery

open access: yesAdvanced Energy Materials, EarlyView.
Halide segregation (HS) in mixed‐halide wide‐bandgap (WBG) perovskites is key to the stability of perovskite‐based tandem cells and a central focus of large‐scale research efforts. Here, we find that the underlying reason for the poor stability of cells prone to HS is enhanced ionic losses during operation. Furthermore, we identified irreversible ionic
Nikhil Kalasariya   +24 more
wiley   +1 more source

Wearable Online Freezing of Gait Detection and Cueing System

open access: yesBioengineering
This paper presents a real-time wearable system designed to assist Parkinson’s disease patients experiencing freezing of gait episodes. The system utilizes advanced machine learning models, including convolutional and recurrent neural networks, enhanced ...
Jan Slemenšek   +5 more
doaj   +1 more source

Computer Vision Pipeline for Image Analysis for Freeze‐Fracture Electron Microscopy: Rosette Cellulose Synthase Complexes Case

open access: yesAdvanced Intelligent Discovery, EarlyView.
This paper presents a computer vision (deep learning) pipeline integrating YOLOv8 and YOLOv9 for automated detection, segmentation, and analysis of rosette cellulose synthase complexes in freeze‐fracture electron microscopy images. The study explores curated dataset expansion for model improvement and highlights pipeline accuracy, speed ...
Siri Mudunuri   +6 more
wiley   +1 more source

VAE+DDPG: An Attention‐Enhanced Variational Autoencoder for Deep Reinforcement Learning‐Based Autonomous Navigation in Low‐Light Environments

open access: yesAdvanced Intelligent Systems, EarlyView.
Variational Autoencoder+Deep Deterministic Policy Gradient addresses low‐light failures of infrared depth sensing for indoor robot navigation. Stage 1 pretrains an attention‐enhanced Variational Autoencoder (Convolutional Block Attention Module+Feature Pyramid Network) to map dark depth frames to a well‐lit reconstruction, yielding a 128‐D latent code ...
Uiseok Lee   +7 more
wiley   +1 more source

Levodopa ONOFF-state freezing of gait: Defining the gait and non-motor phenotype

open access: yesPLoS ONE, 2022
Background Freezing in the levodopa-medicated-state (ON-state) is a debilitating feature of Parkinson’s disease without treatment options. Studies detailing the distinguishing features between people with freezing of gait that improves with levodopa and ...
Reid D. Landes   +4 more
doaj  

Clinical and Biological Determinants of Longitudinal Cognitive Function in Patients With GBA1 Variants and Subthalamic Deep Brain Stimulation

open access: yesAnnals of Neurology, EarlyView.
Objective Whether cognitive decline in patients with Parkinson's disease (PD) carrying GBA1 variants is accelerated after subthalamic deep brain stimulation (STN‐DBS) remains controversial. Clarifying long‐term cognitive outcomes is essential for informed decision making.
Moritz A. Loeffler   +8 more
wiley   +1 more source

Translating Biomedical Research to Medical Devices: A Practical Guide and the Arteriovenous Graft Case Study

open access: yesAdvanced NanoBiomed Research, EarlyView.
Despite significant advances, most academic research fails to result in medical products that benefit patients. This guide shares five key steps to help researchers close that gap: set clear goals, test thoroughly, protect ideas, build diverse teams, and partner with industry.
Cristina Oldani   +4 more
wiley   +1 more source

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