Results 101 to 110 of about 167,453,479 (294)

Model-based 3D gait biometrics

, 2011
There have as yet been few gait biometrics approaches which use temporal 3D data. Clearly, 3D gait data conveys more information than 2D data and it is also the natural representation of human gait perceived by human.
Mark S. Nixon, Nixon, Mark, Ariyanto, Gunawan, Gunawan Ariyanto   +3 more
core   +1 more source

Targeting CXCR2 in Nociceptive Sensory Neurons Offers Novel Therapeutic Potentials for Postoperative Pain

Advanced Science, EarlyView.
Tissue incision induces CXCL5 release, which activates neuronal CXCR2 on incision‐innervating sensory neurons. Neuronal CXCR2 couples with TRPA1 to drive mechanical pain and engages p38 MAPK signaling to upregulate TRPV1 and promote heat pain. Targeted Cxcr2 knockdown relieves incisional pain while preserving CXCR2‐dependent neutrophil responses ...
Yushuang Pan, Peiyi Li, Yufeng Chen, Zishan Dong, Yuanyuan Li, Boyu Liu, Yan Tai, Chuan Wang, Jianqiao Fang, Chengyu Yin, Boyi Liu   +10 more
wiley   +1 more source

A Multidimensional Engineering Strategy Reprograms Microglia via Targeted and Sustained‐Release Extracellular Vesicles for Spinal Cord Injury Repair

Advanced Science, EarlyView.
A multifunctional EV‐based nanoplatform (Ang‐TEVs@Gel) was engineered via preconditioning, surface targeting, and ROS‐responsive hydrogel encapsulation to reprogram microglia. This system restored autophagy via miR‐664a‐3p/PIK3CA axis, cleared myelin debris, resolved neuroinflammation, and promoted axon remyelination, ultimately achieving robust motor ...
Wu Xiong, Minhao Liu, Mingming Zheng, Jizhou Jia, Ziyan Zhu, Guang Kong, Jie Liu, Juan Wang, Wenbo Li, Qingyuan Wang, Qian Zhu, Peiran Chan, Tao Qin, Jiayang Wu, Yongjie Zhang, Chunming Tang, Cong Li, Jin Fan   +17 more
wiley   +1 more source

Using gastrocnemius sEMG and plasma α-synuclein for the prediction of freezing of gait in Parkinson's disease patients.

PLoS ONE, 2014
Freezing of gait (FOG) is a complicated gait disturbance in Parkinson's disease (PD) and a relevant subclinical predictor algorithm is lacking. The main purpose of this study is to explore the potential value of surface electromyograph (sEMG) and plasma ...
Xiao-Ying Wang, Wen-Yan Kang, Qiong Yang, Lin-Yuan Zhang, Sheng-Di Chen, Jun Liu   +5 more
doaj   +1 more source

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

Advanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem, Lea Oehlsen, Sedef Ersoy, Jia Li Ye, Natalie Weber, Elisa Mohr, Wilson Agyapong, Junqing Liu, Maximilian Fuchs, Ke Xiao, Christopher Jahn, Reto Eggenschwiler, Tobias Cantz, Julia Beimdiek, Falk F. R. Buettner, Theresia Kraft, Jan Hegermann, Ivonne J. Knorr, Lisa Ernst, Linda Feldbrügge, Resa Puffert, Kevin Schmidt, Christian Bär, Jeannine Hoepfner, Thomas Thum   +24 more
wiley   +1 more source

Freezing During Swimming as a Precursor to Freezing of Gait in Parkinson's Disease. [PDF]

Mov Disord Clin Pract
Caniça V, Pona-Ferreira F, Guerreiro D, Ferreira JJ.   +3 more
europepmc   +3 more sources

A practical method for the detection of freezing of gait in patients with Parkinson’s disease

, 2014
Yuri Kwon,1 Sang Hoon Park,1 Ji-Won Kim,1 Yeji Ho,1 Hyeong-Min Jeon,1 Min-Jung Bang,1 Gu-In Jung,1 Seon-Min Lee,3 Gwang-Moon Eom,1,2 Seong-Beom Koh,3 Jeong-Whan Lee,1,2 Heung Seok Jeon41Biomedical Engineering, 2Research Institute of Biomedical ...
Lee SM, Ho Y, Jeon HS, Kwon Y, Park SH, Kim JW, Bang MJ, Koh SB, Jeon HM, Jung GI, Eom GM, Lee JW   +11 more
core  

Principles of pathological gait [PDF]

, 2013
Summary: Walking for healthy humans is a basic everyday activity. In patients, especially those with neurologic disorders, the walking pattern can strongly deviate from those of healthy humans.
Schweizer, Katrin Irina
core   +1 more source

A Microenvironment‐Adaptive Scaffold Rejuvenates Peripheral Nerve Regeneration During Aging Via Dual Modulation of Ferroptotic Stimuli in Schwann Cells

Advanced Science, EarlyView.
(i) Aging impairs peripheral nerve regeneration via its dual ferroptosis‐mediated pathologies in senescent schwann cells. (ii) The composite nerve conduit is a symbiosis niche integrating microenvironment‐responsive nanoparticles (Ga‐PTAs) and maxillofacial‐derived mesenchymal stem cells (Mmscs).
Ning Zhan, Lixin Tian, Lianjie Peng, Jingyu Zhang, Lining Lin, Xiaoting Zhang, Yaxian Luo, Zhichao Liu, Xinhua Yao, Mouyuan Sun, Yong He, Mengfei Yu, Huiming Wang   +12 more
wiley   +1 more source

Paroxysmal freezing of gait in a patient with mesial frontal transient ischemic attacks

BMC Neurology, 2017
Background Rare patients have been reported who developed a mixture of gait disturbances following a focal lesion in the frontal lobe. Thus, the exact location of frontal lesion responsible for a specific gait disturbance is not well defined.
Hee Won Hwang, Seung Ha Lee, Chul Hyoung Lyoo, Myung Sik Lee   +3 more
doaj   +1 more source