Results 171 to 180 of about 317,814 (254)

Targeting Immunologic Pathways in Eosinophilic Granulomatosis With Polyangiitis: Translating Emerging Evidence Into Clinical Practice

open access: yesAllergy, EarlyView.
ABSTRACT Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare and potentially life‐threatening systemic, inflammatory disease with multi‐organ manifestations, variable presentation and complex pathology. Multiple interconnected immunological pathways are implicated in EGPA pathology, including a type‐2 immune response driving predominantly ...
Harold Wilson‐Morkeh   +7 more
wiley   +1 more source

Vertical RAS pathway inhibition in pancreatic cancer drives therapeutically exploitable mitochondrial alterations. [PDF]

open access: yesSignal Transduct Target Ther
Hafner P   +28 more
europepmc   +1 more source

Healthy Aging Men Do Not Suffer From Relevant Limitations of Their Reproductive Functions

open access: yesAndrology, EarlyView.
Abstract Background While metabolic disorders are well‐established contributors to testosterone decline and erectile dysfunction (ED), little is known about the natural progression of reproductive parameters in healthy aging men. Objectives This study aimed to evaluate longitudinal changes in reproductive parameters and sought to determine the ...
Simone Bier   +8 more
wiley   +1 more source

Differences and Commonalities of Electrical Stimulation Paradigms After Central Paralysis and Amputation

open access: yesArtificial Organs, EarlyView.
Invasive and non‐invasive functional electrical stimulation (FES) is a well‐established method to partially restore function after paralysis and deliver sensory feedback after amputation. This work summarizes the current state‐of‐the‐art of FES for restoring function, supporting rehabilitation therapy, and assistive devices.
Thomas Stieglitz   +3 more
wiley   +1 more source

Exploring the histopathological signature of repeat‐mediated Fuchs endothelial corneal dystrophy

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To determine the histological differences between Fuchs endothelial corneal dystrophy (FECD) cases with and without the most common genetic risk factor, expansion of a CTG repeat (CTG18.1) within the TCF4 gene. Methods Formalin‐fixed paraffin‐embedded corneal tissues were compared retrospectively, and CTG18.1 status was determined from
Anne‐Marie S. Kladny   +5 more
wiley   +1 more source

Live Podcasting as an Educational Intervention in Dentomaxillofacial Radiology: Controlled Cohort Study.

open access: yesJMIR Med Educ
Hillebrecht AL   +8 more
europepmc   +1 more source

Post‐Banding Ulcer Bleeding After Endoscopic Ligation: Incidence, Risk Factors and Outcomes in Patients With Cirrhosis

open access: yesAlimentary Pharmacology &Therapeutics, EarlyView.
A PBUB is a rare but often fatal complication of endoscopic variceal band ligation. The relevant risk factors contributing to PBUB are unknown and consequently there are no effective preemptive strategies. This study highlights kidney disease as a predictor of PBUB together with the well‐established higher risk for urgent band ligation.
Maria de Brito Nunes   +5 more
wiley   +1 more source

Fatigue in Post-COVID-Condition is accompanied by hypoperfusion of right-occipital areas. [PDF]

open access: yesPLoS One
Hosp JA   +8 more
europepmc   +1 more source

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