Results 191 to 200 of about 165,689 (291)

Mitochondria‐Specific Protein Delivery by Protease‐Triggered Release in Plants with Single‐Walled Carbon Nanotubes

open access: yesAdvanced Materials Technologies, EarlyView.
Polymer‐coated carbon nanotubes were engineered as protease‐responsive nanocarriers for protein delivery in intact plants. GFP cargo can be released by cytosolic phytaspase cleavage and subsequently targeted to mitochondria via an N‐terminal sequence, enabling controlled intracellular protein delivery without tissue damage and demonstrating stable ...
Simon Sau Yin Law   +3 more
wiley   +1 more source

Perfusion Bioreactor Culture Incorporating Mechanical Confinement Enhances Mesenchymal Stem Cell Extracellular Vesicle Production and Wound Healing Potential

open access: yesAdvanced Materials Technologies, EarlyView.
Scalable manufacturing challenges and limited potency remain two of the most intransigent issues limiting clinical translation of EV therapeutics. Mechanical cues can induce phenotypic changes and increased vesiculation in EV source cells without the use of extraneous reagents, chemicals, and/or cargo, thereby potentially drastically improving the ...
Emily H. Powsner   +10 more
wiley   +1 more source

Lattice Structures for Bone Replacement: The Intersection of Bone Biomechanics, Lattice Design, and Additive Manufacturing

open access: yesAdvanced Materials Technologies, EarlyView.
This review outlines how understanding bone's biology, hierarchical architecture, and mechanical anisotropy informs the design of lattice structures that replicate bone morphology and mechanical behavior. Additive manufacturing enables the fabrication of orthopedic implants that incorporate such structures using a range of engineering materials ...
Stylianos Kechagias   +4 more
wiley   +1 more source

Tunable Applicator for Microneedle‐Based Medical Devices

open access: yesAdvanced Materials Technologies, EarlyView.
This paper presents a simple, low‐cost tunable applicator (TAPP) for microneedle array patches that uses a material‐agnostic controlled‐fracture mechanism to ensure reliable skin penetration and uniform array engagement. The scalable, modular design is compatible with injection molding and 3D printing, can be integrated directly into patches, and is ...
Dan Ilyn   +9 more
wiley   +1 more source

Polarization‐Sensitive Au‐TiO2 Nanopillars for Tailored Plasmonic Enhanced Light‐Driven Reaction Activity

open access: yesAdvanced Optical Materials, EarlyView.
Manipulating the product generation yield is achieved on a model plasmonic resonance‐driven reaction by tuning the nonthermal effects of localized surface plasmonic resonance on an elliptical Au‐TiO2 nanopillar metasurface. Asymmetric configuration of the elliptical nanopillar array governs the polarization‐dependent optical properties redshifting the ...
Ning Lyu   +6 more
wiley   +1 more source

Vision‐Assisted Avocado Harvesting with Aerial Bimanual Manipulation

open access: yesAdvanced Robotics Research, EarlyView.
This work outlines the design and implementation of a bimanual aerial robot that employs visual perception and learning to detect, reach, and harvest avocados. A new gripper and fixer arm assembly is used to harvest avocados, while visual perception enables the detection of avocados and estimation of their position and orientation for determining ...
Zhichao Liu   +3 more
wiley   +1 more source

On–Off Switchable Micromotors for Use in Steerable Microvehicles

open access: yesAdvanced Robotics Research, EarlyView.
Electrically controllable micromotors and microvehicles are developed by tuning the diffusion of the fuel. Self‐propelled micromotors using bubble propulsion show great promise for miniaturized devices with multiuse purposes such as cargo delivery and sensing. However, there is currently no method to electrically switch the micromotors on or off. Here,
Hugo Severinsson   +3 more
wiley   +1 more source

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