Results 91 to 100 of about 4,059,547 (363)

TECHNOLINGUALISM AND MULTILINGUALISM ON THE WEB 3.0: USBEK ET RICA BLOG [PDF]

Езиков свят
The democratisation of the Internet has given rise to a digital society, the most influential, smart, and cumbersome in the history of humanity. English, the most used language on the Internet, accounts for 49.7% of the linguistic content across all ...
Yohanna Joseph Waliya
doaj   +1 more source

Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays

FEBS Open Bio, EarlyView.
We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul, Alan Strunga, Jiri Damborsky, Zbynek Prokop   +3 more
wiley   +1 more source

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

FEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp, Eszter Kozák, Natália Tőkési, Lilian Kocsis, Anikó Kelemen, Zsuzsanna Geszti, Adriána Kutás, Mariann Harangi, Ágnes Diószegi, Zsolt Rapi, József Balla, Olivier Le Saux, András Váradi, Viola Pomozi   +13 more
wiley   +1 more source

Emergence of chikungunya fever on the French side of Saint Martin island, October to December 2013 [PDF]

, 2014
Sylvie Cassadou, S Boucau, Marion Petit-Sinturel, Patricia Huc, Isabelle Leparc-Goffart, Martine Ledrans   +5 more
openalex   +1 more source

SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1

FEBS Open Bio, EarlyView.
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl, Khawar Amin, Lydia Gabriel, Nils Hampel, Afshin Iram, Julia Hesse, Constanze Wiek, Jasmin Thuy Vy Nguyen, Helmut Hanenberg, Jürgen Scheller, M. Reza Ahmadian, Björn Stork, Doreen M. Floss, Roland P. Piekorz   +13 more
wiley   +1 more source

Le relazioni culturali e intellettuali tra Italia e Francia dalla Grande Guerra al Fascismo. Introduzione

Storicamente, 2018
L’articolo presenta i risultati di un progetto di ricerca italo-francese triennale sui rapporti culturali intellettuali tra Francia e Italia dalla Prima guerra mondiale al Fascismo.
Roberto Bianchi, Patrizia Dogliani, Caterina Zanfi   +2 more
doaj   +1 more source

Cross-evaluation of modelled and remotely sensed surface soil moisture with in situ data in southwestern France [PDF]

, 2010
Clément Albergel, Jean‐Christophe Calvet, Patricia de Rosnay, Gianpaolo Balsamo, Wolfgang Wagner, S. Hasenauer, Vahid Naeimi, Éric Martin, Éric Bazile, F. Bouyssel, J.‐F. Mahfouf   +10 more
openalex   +1 more source

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Interactions between thin‐ and thick‐skinned tectonics at the northwestern front of the Jura fold‐and‐thrust belt (eastern France) [PDF]

, 2008
Herfried Madritsch, Stefan Schmid, Olivier Fabbri   +2 more
openalex   +1 more source

Mycobacterial cell division arrest and smooth‐to‐rough envelope transition using CRISPRi‐mediated genetic repression systems

FEBS Open Bio, EarlyView.
CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point, Wafaa Achache, Janïs Laudouze, Eliana Sepulveda Ramos, Mickaël Maziero, Céline Crauste, Stéphane Canaan, Pierre Santucci   +7 more
wiley   +1 more source