Results 61 to 70 of about 248,537 (242)

Crisis and Security of Criticism [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
In the Philippe Daros’s narration of the history of European literary criticism after the Second World War, three main periods are distinguished. First, a formalist/structuralist period, centered by language and linguistic approaches, which is a negative
Maziar Mohaymeni
doaj  

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

Sertão translated into Danish

open access: yesBrasiliana: Journal for Brazilian Studies, 2012
This text is a transcription of a lecture given by Peter Poulsen, Danish writer and translator, during the event Discovering Brazilian Northeast with the Music by Luiz Gonzaga, which took place at Aarhus University on 26th and 27th of April, 2012.
Peter Poulsen
doaj   +2 more sources

Proust est-il un philosophe ?

open access: yesStudia Romanica Posnaniensia, 2015
Different philosophers pondered on Proust’s novel, including those who formulated a subtle hypothesis that philosophical thought that emerged from the novel went beyond the passages of philosophical character that could be found in Proust’s work.
Luc Fraisse
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

open access: yesMolecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder   +10 more
wiley   +1 more source

'Sclérose du col vésical': An obsolete terminology still used by French literature? [PDF]

open access: yesArab J Urol, 2023
El Anzaoui J   +6 more
europepmc   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

Mohammad Taghi Qiasi and Translation of French Poetry [PDF]

open access: yesپژوهش‌نامۀ انتقادی متون و برنامه‌های علوم انسانی, 2018
Mohammad Taghi Qiasi has been researching in different fields of French language and literature. In addition, he has provided numerous translations from French to Farsi, particularly about the translation French works.
Mitra Raissi Dehkordi
doaj  

Early‐life high‐fat diet exposure increases Achilles tendon stiffness and induces transcriptomic alterations

open access: yesFEBS Open Bio, EarlyView.
Early‐life exposure to a high‐fat diet altered intact Achilles tendons in rat offspring, making them thinner, stiffer, and molecularly distinct even without injury. These findings suggest that developmental high‐fat diet exposure may impair tendon quality and increase susceptibility to mechanical overload or tendon injury later in life.
Heyong Yin   +3 more
wiley   +1 more source

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