Results 61 to 70 of about 1,550,456 (290)
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Indian and French Philosophical Literature: in Search of Wisdom, Spirituality, and Rationalism [PDF]
, 2016 The Indian philosophy is enriched with incredible, spiritual wisdom. Indian history is full of examples where the literature was specially designed to promote “the aim of life”.
Mishra, S. K. (Satendra) +1 more
core
FEBS Open Bio, EarlyView.CRISPRI‐mediated gene silencing and phenotypic exploration in nontuberculous mycobacteria. In this Research Protocol, we describe approaches to control, monitor, and quantitatively assess CRISPRI‐mediated gene silencing in M. smegmatis and M. abscessus model organisms.
Vanessa Point +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Introduction to Forum: The Hemispheric French Atlantic [PDF]
, 2015 “The Hemispheric French Atlantic” begins to suture a transatlantic to a hemispheric spatiality by tracing out the movement of texts, figures, and traditions within a complex and kinetic circulatory system that moves beyond the geometric model imagined by
Burnham, Michelle
core +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Origin and Position of the Translations of Three French “Commentary” by Mohammad Taghi Ghiasi [PDF]
پژوهشنامۀ انتقادی متون و برنامههای علوم انسانی, 2018 Mohammad Taghi Ghiasi started his career of translator with the translation of a number of literary criticism books, including a Commentary on the Red and the Black of Stendhal, a Commentary on The Stanger of Camus and a Commentary on the Nausea of ...
Sara Tabatabae
doaj
Transculturating the modern : Zhang Ruogu\u27s literary life in 1930s Shanghai
, 2016 Zhang Ruogu 張若谷(1905-1967), now known primarily as an urban writer,2 began his literary career by translating and commenting on French literature in newspapers and journals and subsequently published several urban stories.
CHEN, Shuo Win
core
FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
The Upside-Down Mirror, or Reality Caught in the Act [PDF]
Slovo a SmyslThe present contribution, as part of this line of Proustian research that focuses on the specularity and auto-specularity of À la recherche du temps perdu, examines self-reflexive comparisons at a micro- or even nano-level.
Catherine Ébert-Zeminová
doaj +1 more source