Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
Rolling Bearing Fault Diagnosis via Meta-BOHB Optimized CNN-Transformer Model and Time-Frequency Domain Analysis. [PDF]
Sensors (Basel)Wang Y, Jiang H, Tong B, Song S.
europepmc +1 more source
Frequency Domain Analysis and Precision Realization in Deterministic Figuring of Ultra-Precision Shaft Parts. [PDF]
Materials (Basel), 2020 Sun Z, Hu H, Dai Y, Guan C, Tie G, Ou Y.
europepmc +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Frequency Space Correlation Between REITs and Capital Market Indices [PDF]
Several studies have examined real estate investment trust (REIT) co-movement with stocks or bonds using traditional time domain based methods, such as linear regression or correlation.
Terry V. Grissom, Peter Oppenheimer
core
Time and Frequency Domain Analysis of IMU-Based Orientation Estimation Algorithms with Comparison to Robotic Arm Orientation as Reference. [PDF]
Sensors (Basel)Sultan R, Greiser S.
europepmc +1 more source
Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation
Molecular Oncology, EarlyView.How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim +11 more
wiley +1 more source
An exploration of the editing cut as an articulator in film through frequency domain analysis of spectator EEGs. [PDF]
Front NeurosciSanz-Aznar J.
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Damage Detection in Beam Structures Based on Frequency-Domain Analysis Methods for Nonlinear Systems. [PDF]
Sensors (Basel)Zhang W, Guo X, Cheng L, Zhang B.
europepmc +1 more source