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Four fifty-seven focus; Ohio Deferred Compensation 457 focus; Ohio Deferred Compensation four fifty-seven focus; Participant Focus newsletter

open access: yes, 2010
2010, 1st quarter-; Description based on: 1st quarter 2010; title from PDF caption (viewed on Dec. 7, 2010).; At head of title: Ohio Deferred Compensation.; "A publication of the Ohio Deferred Compensation Board."; Harvested from the web on 12/9 ...

core   +4 more sources

A Low-Dropout Voltage Regulator with a Fractional-Order Control [PDF]

open access: yesRadioengineering, 2016
This paper presents a 5 V / 50 mA low-dropout voltage regulator (LDO). The LDO uses a fractional-order control for its regulation loop to achieve a high DC gain (for a tight DC regulation) while avoiding (for a good stability) a high gain at high ...
L. Kadlcik, P. Horsky
doaj  

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

open access: yesMolecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington   +10 more
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Compensation Review Board (CRB) opinions. 2005

open access: yes, 2005
Updated annually; Began in 2003?; Title from home page last rev. Feb. 6, 2007 (publisher's web site, viewed Mar.
Connecticut. Workers' Compensation Commission. Compensation Review Board.
core   +1 more source

A temperature compensation method of measuring frequency for cylindrical vibratory gyroscope in frequency split trimming

open access: yesMATEC Web of Conferences, 2018
In the process of frequency split trimming, the fluctuation of environmental temperature causes a deviation in measuring the natural frequency, which is bigger than the request trimming accuracy.
Hu Youwang   +5 more
doaj   +1 more source

Seismic attenuation compensation with spectral-shaping regularization

open access: yesEarth and Planetary Physics, 2022
Because of the viscoelasticity of the subsurface medium, seismic waves will inherently attenuate during propagation, which lowers the resolution of the acquired seismic records.
QiZhen Du   +3 more
doaj   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

open access: yesMolecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee   +3 more
wiley   +1 more source

Compensation Review Board (CRB) opinions. 2006

open access: yes, 2006
Updated annually; Began in 2003?; Title from home page last rev. Feb. 6, 2007 (publisher's web site, viewed Mar.
Connecticut. Workers' Compensation Commission. Compensation Review Board.
core   +1 more source

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