The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
An improved material-inspired generation algorithm for load frequency control in EV-integrated power systems. [PDF]
Almutairi SZ, Ginidi AR.
europepmc +1 more source
Frequency control of nuclear-renewable hybrid energy systems using optimal PID and FOPID controllers. [PDF]
Hasan R +3 more
europepmc +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Horseshoe bats (Rhinolophus nippon) suppress clutter noise through echolocation frequency control to detect prey. [PDF]
Yoshida S +3 more
europepmc +1 more source
PSO tuned interval type-2 fuzzy logic for load frequency control of two-area multi-source interconnected power system. [PDF]
Soliman AMA, Bahaa M, Mehanna MA.
europepmc +1 more source
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
Low-frequency torsional resonance arising from large inertia load and elastic shaft causes vibration when industrial servo system is working, which degrades the system's performance of motion control.
Xu F(徐方) +2 more
core
Enhanced load frequency control using a novel fractional-order integral-integral-derivative controller optimized by cuckoo catfish optimizer. [PDF]
Barakat M +3 more
europepmc +1 more source
A Hypothesis for Theta Rhythm Frequency Control in CA1 Microcircuits. [PDF]
Skinner FK +4 more
europepmc +1 more source

