Results 261 to 270 of about 24,313,007 (383)
Molecular Oncology, EarlyView.This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau +9 more
wiley +1 more source
Fluctuations in oscillation frequency control spike timing and coordinate neural networks. [PDF]
J Neurosci, 2014 Cohen MX.
europepmc +1 more source
A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner
Molecular Oncology, EarlyView.We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp +13 more
wiley +1 more source
High Frequency Operation of Metal-halide Lamp Controlled by Microcomputer
, 1987 Toshiaki Mizuno, Taro Ishikawa
openalex +2 more sources
Frequency of Drive (Quinclorac) Treatments on Common Bermudagrass Tolerance and on Large Crabgrass Control [PDF]
, 1995 B. J. Johnson
openalex +1 more source
Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma
Molecular Oncology, EarlyView.The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias +12 more
wiley +1 more source
Integrative physiology of fundamental frequency control in birds. [PDF]
J Physiol Paris, 2013 Goller F, Riede T, Riede T.
europepmc +1 more source
Frequency Judgments for Semantic Categories in Amnesics and Normal Controls
, 1994 Stephen Dopkins +2 more
openalex +1 more source
Molecular Oncology, EarlyView.Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley +1 more source
Frequency control of cell cycle oscillators. [PDF]
Curr Opin Genet Dev, 2010 Oikonomou C, Cross FR.
europepmc +1 more source