Results 121 to 130 of about 243,917 (303)

C2α‐carbanion‐protonating glutamate discloses tradeoffs between substrate accommodation and reaction rate in actinobacterial 2‐hydroxyacyl‐CoA lyase

open access: yesFEBS Open Bio, EarlyView.
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn   +4 more
wiley   +1 more source

A study of Schwarz converters for nuclear powered spacecraft [PDF]

open access: yes
High power space systems which use low dc voltage, high current sources such as thermoelectric generators, will most likely require high voltage conversion for transmission purposes.
Schwarze, Gene E., Stuart, Thomas A.
core   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

open access: yesFEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei   +3 more
wiley   +1 more source

Harmonic Klystron Frequency Converter

open access: yesIEEE Transactions on Electron Devices
A new principle for the design of frequency converters, operating at significantly higher power and efficiency than previous devices, is described in this article. The presented solution is implemented as a particular klystron topology for which a new design criterion is formulated through analytical expressions and a specific design procedure.
Alberto Leggieri   +5 more
openaire   +3 more sources

Modular multilevel converter based LCL DC/DC converter for high power DC transmission grids [PDF]

open access: yes, 2015
This paper presents a modular multilevel converter (MMC) based DC/DC converter with LCL inner circuit for HVDC transmission and DC grids. Three main design challenges are addressed.
Aboushady, Ahmed   +2 more
core   +1 more source

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

open access: yesFEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman   +4 more
wiley   +1 more source

Development of human monoclonal antibodies against TARM1 by yeast display

open access: yesFEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe   +5 more
wiley   +1 more source

The Application Three-phase to Single-phase Z-Source Matrix Converter in Wind Turbine [PDF]

open access: yesJournal of Intelligent Procedures in Electrical Technology, 2017
In this paper a new idea of direct three-phase to single-phase Z-source matrix converter (impedance-source matrix converter) applicable in stand-alone wind turbine is introduced.
vahid asadi rad   +2 more
doaj  

Voltage to Frequency Converter: Modeling and Design [PDF]

open access: yes, 2012
In this thesis a study on conventional voltage to frequency converter is given. A linear voltage to frequency converter is assumed i.e. the output frequency level changes with the varying input voltage level.
Barik, Rajesh Kumar   +1 more
core  

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

open access: yesFEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake   +4 more
wiley   +1 more source

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