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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

The enigma of frequency-dependent selection [PDF]

open access: possibleTrends in Ecology & Evolution, 1998
Frequency-dependent selection is so fundamental to modern evolutionary thinking that everyone `knows' the concept. Yet the term is used to refer to different types of selection. The concept is well defined in the original context of population genetics theory, which focuses on short-term evolutionary change.
Heino, M., Metz, J.A.J., Kaitala, V.
openaire   +4 more sources
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Frequency‐dependent tree growth depends on climate

Ecology, 2021
AbstractClimate and competition interact to affect species’ performance, such as growth and survival, and help determine species distributions and coexistence. However, it is unclear how climatic conditions modulate frequency‐dependent performance, that is, how performance changes as a species becomes locally rare or common.
Jeffrey M. Diez   +3 more
openaire   +2 more sources

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