Results 41 to 50 of about 5,425,503 (237)

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

FEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana, Avigail Yariv, Tal Oppenheim, Hadar Amartely, Dana Reichmann, Oded Livnah   +5 more
wiley   +1 more source

A Holistic Platform Approach for Developing Robust Pulmonary mRNA Delivery: Integrating Novel Phenolic Acid‐Derived Ionizable Lipids and Device Engineering

Advanced Functional Materials, EarlyView.
An integrated pulmonary mRNA delivery platform combining novel biodegradable syringic acid‐derived ionizable lipids, design‐of‐experiments formulation optimization, and vibrating‐mesh nebulizer engineering enabled stable aerosolization and efficient lung delivery.
Neha Kaushal, Younan Ma, Asad Khanmohammed, Dipen Parande, Hanming Zhang, Saket Dolare, Juliet Chen, Apiwat Wangweerawong, Saswata Karmakar, Hongfeng Deng, Frank Koppenhagen, Shraddha Sharma, Eric Reyes, Sherry He, Lianne Boeglin, Caroline Woo, Azadeh Paksa, Ayed Allawzi, Anusha Dias, Gregory Troiano, Shrirang Karve, Frank DeRosa   +21 more
wiley   +1 more source

Frequency diverse array beampattern synthesis method with low sidelobes by integrating mayfly algorithm and convex programming

Electronics Letters, 2023
The range‐angle coupling characteristics of traditional frequency diverse array (FDA) will deteriorate target localization performance. To address this problem, several decoupling methods for FDA have been developed in the past decade, mainly including ...
Mengxuan Xiao, Xiaolang Shao, Taiyang Hu, Jinyu Zhang, Zelong Xiao   +4 more
doaj   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

Design of frequency invariant beamformer for broadband arrays [PDF]

, 2007
A simple method for the design of a class of arrays with frequency invariant beam patterns is proposed. Starting from the desired frequency invariant beam pattern of an n-D array, the proposed method uses a series of substitutions and an n-D inverse ...
Weiss, Stephan, Stephan Weiss, Liu, Wei, Weiss, S., Liu, W., Wei Liu   +5 more
core   +4 more sources

FDA-MIMO Beampattern Synthesis with Hamming Window Weighted Linear Frequency Increments

International Journal of Aerospace Engineering, 2020
By utilizing a tiny frequency increment across the array elements, frequency diverse array (FDA) generates a beampattern possessing the property of range-angle-dependent.
Ming Tan, Chunyang Wang, Hui Yuan, Juan Bai, Lei An   +4 more
doaj   +1 more source

Range-angle-dependent beamforming for FDA radar with Hamming interelement spacing and sinusoidal multicarrier approach

AIP Advances, 2023
By employing a tiny frequency offset across the array elements, a frequency diverse array (FDA) produces a beampattern with the property of being range-angle-dependent.
Ming Tan, Lei Bao, Hang Zhu, Wei Song, Xinmei Wang   +4 more
doaj   +1 more source

Target acquisition and tracking in Frequency Diverse Array radar systems

, 2016
Frequency Diverse Array (FDA) concepts, first introduced in 2006, present a novel approach to electronic beam steering. FDA differs from other conventional arrays in that it applies a small frequency increment to the center frequency for each individual ...
Ozkazanc, Yakup, Altunok, Mustafa, Mustafa Altunok, Yakup Ozkazanc   +3 more
core   +1 more source

Frequency diverse array with random logarithmically increasing frequency offset

, 2020
The frequency diverse arrays (FDAs) have been extensively investigated since it can provide a unique angle‐range‐dependent beampattern. This range‐dependent characteristic can suppress the range ambiguous clutters, leading to many novel potential Radar ...
Ding, Yuan, Ouyang, Shan, Fusco, Vincent; id_orcid, Huang, Gaojian, Fusco, Vincent F., Gaojian Huang, Yuan Ding, Ding, Yuan; id_orcid, Shan Ouyang, Vincent Fusco   +9 more
core   +1 more source

Magnetically Driven Biofabrication for Tissue Engineering: From Nanoparticle Design to Mag‐ATMP Translation

Advanced Healthcare Materials, EarlyView.
Magnetically responsive nanoparticles enable remote control over biomaterials, cells, and engineered tissues. This review summarizes material design, biological safety, fabrication and actuation strategies, computational validation, and translational pathways that support the development of magnetic tissue‐engineering platforms and future magnetically ...
Konstantinos Ioannidis, Dimitrios Lefas, Maya Guilliams, Jackie Van Grootenbril, Isaak Decoene, Dimitrios Sakellariou, Bart Smeets, Stefanos Mourdikoudis, Ioannis Papantoniou   +8 more
wiley   +1 more source