Results 91 to 100 of about 1,467 (253)

Audio Signal Processing Using Time Domain Mel-Frequency Wavelet Coefficient

open access: yes
Extracting features from the speech is the most critical process in speech signal processing. Mel Frequency Cepstral Coefficients (MFCC) are the most widely used features in the majority of the speaker and speech recognition applications, as the filtering in this feature is similar to the filtering taking place in the human ear.
Sebastian, Rinku   +2 more
openaire   +2 more sources

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Terahertz spectroscopy of diabetic and non-diabetic human blood plasma pellets. [PDF]

open access: yesJ Biomed Opt, 2021
Lykina AA   +16 more
europepmc   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Multipath/RFI/modulation study for DRSS-RFI problem: Voice coding and intelligibility testing for a satellite-based air traffic control system [PDF]

open access: yes
Analog and digital voice coding techniques for application to an L-band satellite-basedair traffic control (ATC) system for over ocean deployment are examined.
Birch, J. N., Getzin, N.
core   +1 more source

Effect of chemotherapy on passenger mutations in metastatic colorectal cancer

open access: yesMolecular Oncology, EarlyView.
Changes in passenger mutation load and predicted immunotherapy response after chemotherapy treatment. Tumor cells rich with passenger mutations have increased sensitivity to chemotherapy. Correlation of passenger mutations with neoantigen load suggests highly mutated clones promote a more effective response to immunotherapy, and therefore, first‐line ...
Marium T. Siddiqui   +6 more
wiley   +1 more source

Evidential Evolving Gustafson-Kessel Algortithm (E2GK) and its application to PRONOSTIA's Data Streams Partitioning.

open access: yes, 2011
International audienceCondition-based maintenance (CBM) appears to be a key element in modern maintenance practice. Research in diagnosis and prognosis, two important aspects of a CBM program, is growing rapidly and many studies are conducted in research
Bauer, Olivier   +4 more
core   +1 more source

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