Results 81 to 90 of about 1,483,139 (351)
Filtering technique based on high-frequency plant modeling for high-gain control [PDF]
, 1979 This invention was an improvement in aircraft control systems that utilized feedback motion sensors to generate a signal to control the aircraft. The improvement consisted essentially of a complementary filter comprising a simplified model of the ...
Garren, J. F., Jr., Niessen, F. R.
core +1 more source
The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity
Molecular Oncology, EarlyView.Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli +7 more
wiley +1 more source
Real-Time Filter Method Based on the Structural Frequency of FAST Cabin-Cable System
Advances in Mechanical Engineering, 2014 Due to great flexibility, low damping, and variable structure in the cabin-cable system of five hundred meter Aperture Spherical Radio Telescope (FAST), a real-time digital low-pass filter based on the analysis of frequency is presented in this paper ...
Wenhua Xu +3 more
doaj +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers
Molecular Oncology, EarlyView.This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel +6 more
wiley +1 more source
HIL modeling of systems using the multipole filter
Омский научный вестникThe article proposes an interface (multipole filter) that provides stability of the semi-natural modelling of the initial systems when the fragments of the system are represented by N-poles connected with each other by high intensity loopback (HIL).Thus,
M. N. Maksimov, S. M. Maksimova
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Reconfigurable Ring Filter with Controllable Frequency Response
The Scientific World Journal, 2014 Reconfigurable ring filter based on single-side-access ring topology is presented. Using capacitive tuning elements, the electrical length of the ring can be manipulated to shift the nominal center frequency to a desired position.
Norfishah Ab Wahab +3 more
doaj +1 more source