Results 91 to 100 of about 3,181,689 (295)

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Control-enhanced non-Markovian quantum metrology

Communications Physics
Quantum metrology promises unprecedented precision of parameter estimation, but it is often vulnerable to noise. While significant efforts have been devoted to improving the metrology performance in Markovian environments, practical control schemes ...
Xiaodong Yang, Xinyue Long, Ran Liu, Kai Tang, Yue Zhai, Xinfang Nie, Tao Xin, Jun Li, Dawei Lu   +8 more
doaj   +1 more source

High-Accuracy Frequency Standard Comparison Technology Combining Adaptive Frequency and Lissajous Figure

IEEE Open Journal of Instrumentation and Measurement
To meet the requirements of high-precision measurement of time-frequency multiparameters, a high-accuracy frequency standard comparison technology combining adaptive frequency and Lissajous figure is proposed.
Baoqiang Du, Yangfan Su, Zerui Yang
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Simultaneous measurement of multiple incompatible observables and tradeoff in multiparameter quantum estimation

npj Quantum Information
How well can multiple incompatible observables be implemented by a single measurement? This is a fundamental problem in quantum mechanics with wide implications for the performance optimization of numerous tasks in quantum information science.
Hongzhen Chen, Lingna Wang, Haidong Yuan
doaj   +1 more source

The measurement of frequency and frequency stability of precision oscillators [PDF]

The specification and performance of precision oscillators is discussed as a very important topic to the owners and users of these oscillators. This paper presents at the tutorial level some convenient methods of measuring the frequencies of precision ...
Allan, D. W.
core   +1 more source

2S hyperfine structure of atomic deuterium

, 2004
We have measured the frequency splitting between the $(2S, F=1/2)$ and $(2S, F=3/2)$ hyperfine sublevels in atomic deuterium by an optical differential method based on two-photon Doppler-free spectroscopy on a cold atomic beam.
F. Biraben, H. A. Bethe, N. Kolachevsky, N. Ramsey, P. Fendel, S. G. Karshenboim, S. G. Karshenboim, T. W. Hänsch   +7 more
core   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Single photon continuous variable quantum key distribution based on energy-time uncertainty relation

, 2006
In previous quantum key distribution (QKD) protocols, information is encoded on either the discrete-variable of single-photon signal or continuous-variables of multi-photon signal. Here, we propose a new QKD protocol by encoding information on continuous-
Assche, Bing Qi, Donnelly, Ekert, Gisin, Gisin, Gobby, Grosshans, Hillery, Hughes, Hwang, Jiang, Lo, Lodewyck, Marand, Molotkov, Molotkov, Muller, Nazarathy, Shi, Zhang, Zhao   +21 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source