Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
Low-Cost Voltage Zero-Crossing Detector for AC-Grid Applications
Electrical, Control and Communication Engineering, 2014 Renewable energy sources and energy storage devices are becoming more popular. Some of them like small hydropower turbines, wind turbines and diesel generators produce AC voltage with different frequency and voltage than the main grid.
Vorobyov Maxim, Vitols Kristaps
doaj +1 more source
High-frequency measurement of concentration in an isothermal methane-air gas mixture using spontaneous Raman spectroscopy. [PDF]
Sci Rep, 2023 Rodrigues J +3 more
europepmc +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
High-Accuracy Phase Frequency Detection Technology Based on BDS Time and Frequency Signals
SensorsFor the time and frequency signals of Beidou satellites, a high-accuracy phase frequency detection technology based on phase group synchronization is proposed.
Baoqiang Du, Lanqin Tan
doaj +1 more source
FEBS Letters, EarlyView.Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman +2 more
wiley +1 more source
Feature-Based Characterisation of Turned Surface Topography with Suppression of High-Frequency Measurement Errors. [PDF]
Sensors (Basel), 2022 Podulka P.
europepmc +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Reconstruction of periodic signals using neural networks
Tecnura, 2014 In this paper, we reconstruct a periodic signal by using two neural networks. The first network is trained to approximate the period of a signal, and the second network estimates the corresponding coefficients of the signal's Fourier expansion.
José Danilo Rairán Antolines
doaj
High-Resolution Magnetoelectric Sensor and Low-Frequency Measurement Using Frequency Up-Conversion Technique. [PDF]
Sensors (Basel), 2023 Sun K +7 more
europepmc +1 more source