Results 81 to 90 of about 3,181,689 (295)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Entanglement-enhanced quantum lock-in detection achieving Heisenberg scaling

Nature Communications
Quantum lock-in detection (QLID) is a powerful technique for extracting weak oscillating signals within noise. While entanglement may enhance measurement precision beyond the standard quantum limit (SQL), its integration with QLID is still an ...
J.-W. Zhang, M. Zhuang, B. Wang, W.-F. Yuan, J.-C. Li, G.-Y. Ding, W.-Q. Ding, L. Chen, S.-J. Chen, F. Zhou, C. Lee, M. Feng   +11 more
doaj   +1 more source

Noise characterization of an Optical Frequency Comb using Offline Cross-Correlation

, 2016
Using an offline cross-correlation technique, we have analyzed the noise behavior of a new type of optical frequency comb (OFC), which is carrier envelope offset (CEO) free by configuration, due to difference frequency generation.
Champenois, Caroline, Collombon, Mathieu, Ferrand, Didier, Guyomarc'h, Didier, Hagel, Gaëtan, Houssin, Marie, Khayatzadeh, Ramin, Knoop, Martina, Morizot, Olivier   +8 more
core   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Dispersive Charge and Flux Qubit Readout as a Quantum Measurement Process

, 2006
We analyze the dispersive readout of superconducting charge and flux qubits as a quantum measurement process. The measurement oscillator frequency is considered much lower than the qubit frequency. This regime is interesting because large detuning allows
Johansson, G., Tornberg, L.
core   +2 more sources

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source

The Roadmap of 2D Materials and Devices Toward Chips

Nano-Micro Letters
Highlights This review introduces the potential of 2D electronics for post-Moore era and discusses their current progress in digital circuits, analog circuits, heterogeneous integration, sensing circuits, artificial intelligence chips, and quantum chips ...
Anhan Liu, Xiaowei Zhang, Ziyu Liu, Yuning Li, Xueyang Peng, Xin Li, Yue Qin, Chen Hu, Yanqing Qiu, Han Jiang, Yang Wang, Yifan Li, Jun Tang, Jun Liu, Hao Guo, Tao Deng, Songang Peng, He Tian, Tian-Ling Ren   +18 more
doaj   +1 more source

A Flexible Photonic Method for Angle-of-Arrival and Frequency Measurements

Photonics
A microwave photonic approach for measuring the angle of arrival (AOA) and frequency is proposed and experimentally demonstrated. The AOA-dependent phase difference and frequency of two received signals were mapped to intensity information through ...
Yunkun Luo, Yang Jiang, Jing Xu, Xiaohong Lan, Jinjian Feng, Jiancheng Yu, Qianyou Long, Tingyi Jiang, Hui Zhang, Yu Wu   +9 more
doaj   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Photonic-Assisted Multi-Tone Microwave Frequency Measurement Based on Pulse Identification

Photonics
We report a photonic-assisted method for measuring the frequencies of a multi-tone microwave with high accuracy based on pulse identification. The unknown microwave signal and a linearly chirped signal are modulated to an optical carrier using a dual ...
Xiaobing Xie, Chao Luo, Huiyun Tang, Jinfeng Du, Ming Li, Wei Li   +5 more
doaj   +1 more source