Results 131 to 140 of about 2,112,118 (259)
Research on the Method of Frequency Measurement Based on Pulse Width Measurement [PDF]
Proceedings of the 8th International Conference on Social Network, Communication and Education (SNCE 2018), 2018 openaire +1 more source
Molecular Oncology, EarlyView.RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Quadri-Wave Lateral Shearing Interferogram Outpainting Using QW-GAN for Accurate Wavefront Reconstruction. [PDF]
Sensors (Basel)Fan Y, Duan Y, Zhang Y, Da Z, Yue Y.
europepmc +1 more source
Molecular Oncology, EarlyView.This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Time-Frequency Feature Extraction and Modal Component Reconstruction for Structural Dynamic Monitoring Using MTM-eNTFT. [PDF]
Entropy (Basel)Li L, Wang J, Zhang C.
europepmc +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Loose Particle Material Identification for Sealed Electronic Devices Using Pulse Endpoint Detection and CEEMDAN Feature Optimization. [PDF]
Sensors (Basel)Ren Z, Wang K, Lu Y, Song S, Zou X.
europepmc +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
High-Order Derivative Detection for FSK Ambient Backscatter Communications in Edge-Intelligent Sensing Systems. [PDF]
Sensors (Basel)Wu J, Wei P, Xiao S, Wang J, Tang W.
europepmc +1 more source
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source