Results 31 to 40 of about 4,234 (257)

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

open access: yesFEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng   +8 more
wiley   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

open access: yesFEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Capacity of Time-Hopping PPM and PAM UWB Multiple Access Communications over Indoor Fading Channels

open access: yesEURASIP Journal on Wireless Communications and Networking, 2008
The capacity of time-hopping pulse position modulation (PPM) and pulse amplitude modulation (PAM) for an ultra-wideband (UWB) communication system is investigated based on the multipath fading statistics of UWB indoor wireless channels.
T. Aaron Gulliver, Hao Zhang
doaj   +2 more sources

Robust Frequency-Hopping System for Channels with Interference and Frequency-Selective Fading [PDF]

open access: yes2007 IEEE International Conference on Communications, 2007
A robust frequency-hopping system with noncoherent detection, iterative turbo decoding and demodulation, and channel estimation is presented. The data modulation is the spectrally compact nonorthogonal continuous-phase frequency-shift keying, which strengthens the frequency-hopping system against multiple- access interference and multitone jamming.
Don J. Torrieri   +2 more
openaire   +1 more source

Mitochondrial translation and coordinated cytosolic translation in metabolic homeostasis and disease

open access: yesFEBS Letters, EarlyView.
Mitochondrial function depends on coordinated protein production from the nuclear and mitochondrial genomes. This review highlights how cytosolic and mitochondrial translation, mRNA localization, protein import, and respiratory complex assembly are integrated to maintain mitochondrial proteostasis and function.
Boseon Kim   +4 more
wiley   +1 more source

Transmit scheme for GLSFBC-CDMA-OFDMA system

open access: yesTongxin xuebao, 2012
A novel GLSFBC (group layered SFBC)-CDMA-OFDMA multiple antenna transmit scheme was proposed over frequency-selective fading channels.The proposed scheme is based on a three-level design of cascade codes:the first level(based on OFDMA)deals with multi ...
Jin-long ZHAN, Jian-jun LU, Guang-yue LU
doaj   +2 more sources

Channel and delay estimation for base-station-based cooperative communications in frequency-selective fading channels

open access: yesSouth African Journal of Science, 2011
A channel and delay estimation algorithm for both positive and negative delay, based on the distributed Alamouti scheme, has been recently discussed for base-station-based asynchronous cooperative systems in frequency-flat fading channels.
Hongjun Xu, Laneil Padayachee
doaj  

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

open access: yesMolecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur   +11 more
wiley   +1 more source

Effective capacity channel model for frequency-selective fading channels [PDF]

open access: yesWireless Networks, 2005
To efficiently support quality of service (QoS) in future wireless networks, it is important to model a wireless channel in terms of connection-level QoS metrics such as data rate, delay and delay-violation probability. To achieve this, in [7], we proposed and developed a link-layer channel model termed effective capacity (EC) for flat fading channels.
Dapeng Wu 0001, Rohit Negi
openaire   +1 more source

FREQUENCY DOMAIN EQUALIZATION TECHNIQUES FOR MULTICODE DS-CDMA IN FREQUENCY SELECTIVE RAYLEIGH FADING CHANNEL

open access: yesJournal of Engineering, 2010
Orthogonal multicode direct sequence code division multiple access (DS-CDMA) has the flexibility in offering high data rate services. However, in a frequency-selective fading channel, the bit error rate (BER) performance is severely degraded since the ...
Maha George Zia, Sameer Akram Dawood
doaj   +1 more source

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